Results 71 to 80 of about 535,763 (276)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Arnfried Antonius, coral diseases, and the AMLC

Revista de Biología Tropical, 2012
The study of coral diseases, coral pathogens, and the effects of diseases on tropical and subtropical coral reefs are all current, high-profile research areas. This interest has grown steadily since the first report of a coral disease in 1973. The author
Laurie L. Richardson
doaj   +2 more sources

Epimicrobiota associated with the decay and recovery of Orbicella corals exhibiting Dark Spot Syndrome

Frontiers in Microbiology, 2016
Dark Spot Syndrome (DSS) is one of the most common diseases of boulder corals in the Caribbean. It presents as sunken brown lesions in coral tissue, which can spread quickly over coral colonies.
Julie L Meyer, John Mark Rodgers, Brian Alexander Dillard, Valerie J Paul, Max eTeplitski   +4 more
doaj   +1 more source

Notes on the Biology of \u3ci\u3eSaperda Imitans\u3c/i\u3e Infesting Wind-Damaged Black Cherry in Allegheny Hardwood Stands [PDF]

, 2018
This paper reports observations made on the life history and biology of Saperda imitans Felt & Joutel in black cherry, Prunus serotina Ehrh. S. imitans was the principle longhorned beetle (Coleoptera: Cerambycidae) reared from bolts collected from 68 ...
Allen, Douglas C, DiGirolomo, Marc F, Stehman, Stephen V   +2 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Black phosphorus-Au-thiosugar nanosheets mediated photothermal induced anti-tumor effect enhancement by promoting infiltration of NK cells in hepatocellular carcinoma

Journal of Nanobiotechnology, 2022
Background Hepatocellular carcinoma (HCC) is a heterogeneous cancer required combination therapy, such as photothermal therapy and chemotherapy. In recent years, cancer immunotherapies are rapidly evolving and are some of the most promising avenues to ...
Changchang Jia, Fan Zhang, Jiamei Lin, Liwen Feng, Tiantian Wang, Yuan Feng, Feng Yuan, Yang Mai, Xiaowei Zeng, Qi Zhang   +9 more
doaj   +1 more source

Citrus Canopy SPAD Prediction under Bordeaux Solution Coverage Based on Texture- and Spectral-Information Fusion

Agriculture, 2023
Rapid and nondestructive prediction of chlorophyll content and response to the growth of various crops using remote sensing technology is a prominent topic in agricultural remote sensing research.
Shunshun Ding, Juanli Jing, Shiqing Dou, Menglin Zhai, Wenjie Zhang   +4 more
doaj   +1 more source

Detection of genetic diversity among Indian strains of _Xanthomonas campestris_ pv. _mangiferaeindicae_ using PCR-RAPD [PDF]

, 2008
The randomly amplified polymorphic DNA (RAPD) technique was used to investigate the genetic diversity in 6 strains of _Xanthomonas campestris_ pv. _mangiferaeindicae_ (_Xcmi_), the causal pathogen of mango bacterial canker disease (MBCD).
Ram Kishun, Vijai Kumar Gupta
core   +1 more source

Interactions between N-linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum [PDF]

, 2015
The neuronal serpin neuroserpin undergoes polymerisation as a consequence of point mutations that alter its conformational stability, leading to a neurodegenerative dementia called familial encephalopathy with neuroserpin inclusion bodies (FENIB ...
Dalton, Lucy, Gooptu, Bibek, GUADAGNO, NOEMI ANTONELLA, Irving, James A, Lomas, David A, LUPO, GIUSEPPE, Manno, Mauro, Marciniak, Stefan J, Martorana, Vincenzo, MIRANDA BANOS, MARIA ELENA, MORICONI, CLAUDIA, Noto, Rosina, Ordoñez, Adriana, Timpano, Valentina   +13 more
core   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source