Black-band disease (BBD) is a persistent disease that cause the decline of the coral reef ecosystems, which is still slightly recorded in Indonesia, including in Pari Island, Thousand Islands.
Michael Delpopi +3 more
doaj +1 more source
Nail disorders in skin of color: Approach to onychoscopic diagnosis
Onychoscopy provides a better understanding of nail lesions in terms of diagnosis, monitoring of progression and response to treatment. Author have put forward a simplified way to approach to a nail lesion by onychoscopy.
Balachandra S Ankad +2 more
doaj +1 more source
The Transcriptional Landscape of Marek’s Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes [PDF]
Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that infects chickens and poses a serious threat to poultry health. In infected animals, MDV efficiently replicates in B cells in various lymphoid organs.
Bertzbach, Luca D. +7 more
core +2 more sources
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover. [PDF]
Protein turnover through cullin-3 is tightly regulated by posttranslational modifications, the COP9 signalosome, and BTB/POZ-domain proteins that link cullin-3 to specific substrates for ubiquitylation.
Chen, Ju +3 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Systematic review and meta-analysis of 50 years of coral disease research visualized through the scope of network theory [PDF]
Coral disease research encompasses five decades of undeniable progress. Since the first descriptions of anomalous signs, we have come to understand multiple processes and environmental drivers that interact with coral pathologies.
Luis M. Montilla +3 more
doaj +2 more sources
Assessment of the microbial communities associated with white syndrome and brown jelly syndrome in aquarium corals [PDF]
Bacterial and ciliate assemblages associated with aquarium corals displaying white syndrome (WS) and brown jelly syndrome (BJS) were investigated. Healthy (n = 10) and diseased corals (WS n = 18; BJS n = 3) were analysed for 16S rRNA gene bacterial ...
Bythell, John C. +3 more
core +1 more source
Bacterial symbionts of acroporid corals: Antipathogenic potency against Black Band Disease
Wijayanti DP, Sabdono A, Widyananto PA, Dirgantara D, Hidaka M. 2018. Bacterial symbionts of acroporid corals: Antipathogenic potency against Black Band Disease. Biodiversitas 19: 1236-1242. Black Band Disease (BBD), an infectious coral disease which can cause a rapid decline of coral reefs, has appeared as a serious threat -to many reefs around the ...
DIAH PERMATA WIJAYANTI +4 more
openaire +1 more source

