Results 61 to 70 of about 93,835 (304)
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Farmer's residence on Big Bear Farms [PDF]
, 1962 Black and white photograph of the farmer's residence on Big Bear Farms in Powell, Ohio. According to a letter, written by Wayne E. Brown, in December 1961, "At present two tenants are living in the houses on the farm and handle the cattle feeding and ...
Big Bear
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Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Black Canyon, Bear River [PDF]
, 2001 Color transparency photo of a view of the Bear River in Black Canyon near Grace Power Plant, Caribou County, Idaho, October ...
Denton, Craig, 1947-
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Living with the Florida Black Bear: a Homeowner's Guide to Nuisance Bear Prevention
EDIS, 2007 WEC-215, a 3-page illustrated fact sheet by Kimberly M. Annis, Melvin E. Sunquist, and William M. Giuliano, describes the Florida black bear, its distribution, and the foraging behaviors that bring it in contact with humans, how to prevent nuisance ...
Kimberly M. Annis +2 more
doaj +5 more sources
The urothelium of a hibernator: the American black bear [PDF]
Physiological Reports, 2015 The American black bear undergoes a 3-5 month winter hibernation during which time bears do not eat, drink, defecate, or urinate. During hibernation renal function (GFR) is 16-50% of normal but urine is reabsorbed across the urinary bladder (UB) urothelium thus enabling metabolic recycling of all urinary constituents.
Spector, David A +3 more
openaire +2 more sources
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Parking lot and exterior of Graceland Shopping Center Big Bear location [PDF]
, 1954 Black and white photograph of the parking lot and exterior of the Graceland Shopping Center Big Bear location in July of 1954. Supermarkets introduced many 'firsts' in the ratailing industry to their customers during these years: one-step shopping; new ...
Big Bear
core
Poaching of Asiatic black bear: evidence from Siran and Kaghan valleys, Pakistan
Global Ecology and Conservation, 2020 This paper assesses the vulnerability of Asiatic black bear to poaching in a key ecological zone in Northern Pakistan. Evidence about black bear hunting and cubs poaching were collected from Siran and Kaghan valleys of district Mansehra, Khyber ...
Zaib Ullah +4 more
doaj +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source