Quantification of Actaea racemosa L. (black cohosh) from some of its potential adulterants using qPCR and dPCR methods [PDF]
Scientific Reports, 2021 The demand for popular natural health products (NHPs) such as Black Cohosh is increasing considerably, which in turn challenges quality assurance (QA) throughout the supply chain.
Jeevitha Shanmughanandhan +4 more
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The effect of black cohosh extract and risedronate coadministration on bone health in an ovariectomized rat model [PDF]
Frontiers in PharmacologyPreparations of black cohosh extract are sold as dietary supplements marketed to relieve the vasomotor symptoms of menopause, and some studies suggest it may protect against postmenopausal bone loss.
Amy L. Inselman +19 more
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On the Biosynthesis of Bioactive Tryptamines in Black Cohosh (Actaea racemosa L.) [PDF]
PlantsBotanical dietary supplements are widely used, but issues of authenticity, consistency, safety, and efficacy that complicate their poorly understood mechanism of action have prompted questions and concerns in the popular and scientific literature.
Martin J. Spiering +2 more
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GnRH-a-Induced Perimenopausal Rat Modeling and Black Cohosh Preparations’ Effect on Rat’s Reproductive Endocrine [PDF]
Frontiers in Endocrinology, 2021 BackgroundEndometriosis (EMS) is an estrogen-dependent disease, which easily recurs after operation. Gonadotropin-releasing hormone agonist (GnRH-a), an estrogen-inhibiting drug, can effectively inhibit the secretion of gonadotropin by pituitary gland ...
Jiming Chen +11 more
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Benefits of Black Cohosh (Cimicifuga racemosa) for Women Health: An Up-Close and In-Depth Review [PDF]
Pharmaceuticals, 2022 Women’s health is an imminent concern worldwide, but it remains an ignored segment of research in most developing countries, and is yet to take the center stage in even developed nations.
Sradhanjali Mohapatra +7 more
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Quality by Design Assisted Optimization and Risk Assessment of Black Cohosh Loaded Ethosomal Gel for Menopause: Investigating Different Formulation and Process Variables [PDF]
Pharmaceutics, 2023 Black cohosh (Cimicifuga racemosa) (CR) is a popular herb and is medically lauded for ameliorating myriad symptoms associated with menopause. However, its pharmaceutical limitations and non-availability of a patient-compliant drug delivery approach have ...
Sradhanjali Mohapatra +6 more
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Exploring the Efficacy and Safety of Black Cohosh (Cimicifuga racemosa) in Menopausal Symptom Management [PDF]
Journal of Mid-Life HealthBlack cohosh (Cimicifuga racemosa) is a perennial plant used to treat menopause. This plant is known to have a serotonergic rather than estrogenic impact. It has been recommended to treat vasomotor symptoms associated with breast cancer patients. It also
Kritiksha Hedaoo +4 more
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Structure-Guided Identification of Black Cohosh (Actaea racemosa) Triterpenoids with In Vitro Activity against Multiple Myeloma [PDF]
Molecules, 2020 Black cohosh is a well-established medicinal plant and preparations of its rootstock are used for the treatment of mild climacteric complaints. The compounds considered responsible for the therapeutic effect are triterpene glycosides, characterized by a ...
Karin Jöhrer +3 more
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Black Cohosh and Liver Toxicity: Is There a Relationship? [PDF]
Case Reports in Gastrointestinal Medicine, 2014 Herbal supplements are commonly used by patients for various problems. It is a well-known fact that most patients do not tell their physicians about the use of herbal supplements unless they are specifically asked.
Mohammed Muqeet Adnan +5 more
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Black Cohosh Hepatotoxicity with Autoimmune Hepatitis Presentation [PDF]
Case Reports in Gastroenterology, 2017 Herbal medicines have been used for the treatment of various ailments since time immemorial. Black cohosh (BC) is well known for the treatment of postmenopausal symptoms, with conflicting evidence supporting its safety and benefits.
Diana L. Franco +3 more
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