Results 41 to 50 of about 100,881 (268)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Using very-long-baseline interferometry (VLBI) observations at (sub)millimeter wavelengths, the Event Horizon Telescope (EHT) currently achieves the finest angular resolution of any astronomical facility, necessary for imaging the horizon-scale structure
Uri Rolls +5 more
doaj +1 more source
Many black-hole sources emit a substantial fraction of their luminosities in blackbody-like spectral components. It is usual to assume that these are produced in regions at least comparable in size to the hole's Schwarzschild radius, so that a measure of the emitting area provides an estimate of the black hole mass M. However there is then no guarantee
King, AR, Puchnarewicz, EM
openaire +3 more sources
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
The radial distribution function reveals the underlying mesostructure of the AdS black hole
Based on the equations of state, one can infer the underlying interaction potentials among the black hole molecules in the case of Schwarzschild-AdS and charged AdS black holes.
Conghua Liu, Jin Wang
doaj +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Multimessenger Probes of Supermassive Black Hole Spin Evolution
Using the semianalytic model Serotina , we investigate the cosmic spin evolution of supermassive black holes (SMBHs) incorporating recent results from general-relativistic magnetohydrodynamics simulations of spin-down from relativistic jets.
Angelo Ricarte +3 more
doaj +1 more source
The dynamics of Liouville fields coupled to gravity are investigated by applying the principle of general covariance to the Liouville action in the context of a particular form of two-dimensional dilaton gravity. The resultant field equations form a closed system for the Liouville/gravity interaction.
openaire +3 more sources
This study investigates laser shock peening for enhancing fatigue performance of riveted aerospace aluminum joints. A comparative approach with cold expansion combines fatigue testing and synchrotron X‐ray methods. Integrating mechanical testing with residual stress and strain characterization provides insights into how different treatments affect the ...
Ogün Baris Tapar +6 more
wiley +1 more source
The Event Horizon Telescope (EHT) has produced resolved images of the supermassive black holes (SMBHs) Sgr A* and M87*, which present the largest shadows on the sky.
Xinyue Alice Zhang +8 more
doaj +1 more source

