Results 131 to 140 of about 1,717 (222)

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

A reliable score-based routing protocol using a fog-assisted intrusion detection system in vehicular ad-hoc networks. [PDF]

Sci Rep
Tahajomi Banafshehvaragh S, Zarei M, Rahmani AM.   +2 more
europepmc   +1 more source

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

Advanced Science, EarlyView.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen, Shuyang Yao, Sihui Cheng, Jiayi Tian, Ang Li, Yusen Yan, Xiang Zhang, Yuanjing Liu, Yumeng Wang, Qichen Cao, Chenglin Miao   +10 more
wiley   +1 more source

Weighting Material in Drilling Fluids: Sagging Mechanisms, Influencing Factors, and Prevention Strategies. [PDF]

ACS Omega
Li MC, Yang D, Sun J, Lv K, Zhang Y, Shen H, Wang Q, Liu C.   +7 more
europepmc   +1 more source

Characterization of binary black holes by heterogeneous gravitational-wave networks

, 2018
S. Vitale, C. Whittle
openalex   +2 more sources

Millimeter Observation of Black Hole Microquasars: Radio Timing with Korean VLBI Network [PDF]

, 2004
Jeong-Sook Kim, Soon-Wook Kim
openalex   +1 more source

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

Advanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang, Xiayan Chu, Xuerui Wang, Wenkun Zhang, Jinnuo Lu, Chuting Xu, Shoucheng Hu, Guoyu Pan, Chih‐Tsung Yang, Xiaohui Zhang, Shaojin Li, Zhaobin Guo, Hanyang Liu, Guangbo Ge   +13 more
wiley   +1 more source

Unveiling the neuroprotective potential of Ipomoea carnea ethanol extract via the modulation of tau and β-secretase pathways in AlCl₃-induced memory impairment in rats in relation to its phytochemical profiling. [PDF]

Inflammopharmacology
El-Kashak WA, Essa AF, Abdelhameed MF, Ahmed YH, Abd Elkarim AS, Elghonemy MM, Ibrahim BMM, Gaara AH, Mohamed TK, Elshamy AI.   +9 more
europepmc   +1 more source

A Micro–Black-Hole Network Model for Stable matter density ( Iron regime) , Dark Matter, Energy, and Stability Across Scales — A Theoretical Extension of the "Algorithm of Existence Physic Version, Zenodo 2026 " Framework

Ali Moslemi tabrizi
openalex   +1 more source

Probing primordial black holes and dark matter clumps in the Solar System with gravimeter and Global Navigation Satellite Systems networks [PDF]

Miguel Cuadrat-Grzybowski, Sébastien Clesse, Pascale Defraigne, Michel Van Camp, Bruno Bertrand   +4 more
openalex   +1 more source