Results 101 to 110 of about 3,493,414 (351)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

AFRO-CARIBBEAN WOMEN WRITERS AND THE LITERARY EXPERIENCE: OTHERING AS SYMBOLIC VIOLENCE IN MERLE HODGE’S CRICK CRACK MONKEY

open access: yesRevista Brasileira de Literatura Comparada, 2017
The aim of this essay is to discuss the issue of symbolic violence against the black feminine subject, resulting from the process of ‘Othering’ in the European dominant culture as represented in Merle Hodge’s Crick Crack Monkey.
Norma Diana Hamilton, Cristina Stevens
doaj  

Where is the Place for Black Atlantic Literature and Authorship?

open access: yesJournal of French and Francophone Philosophy
In the wake of Black Atlantic terror, enslavement, colonialism and violence, is there a place for literature? Where is there a place for the author? In other words, to rethink poet Muriel Rukeyser’s question, where is there a place for Black Atlantic ...
Sophia Jahadhmy
doaj   +1 more source

The physical fundamental plane of black hole activity: revisited

open access: yes, 2015
The correlation between the jet power and accretion disk luminosity is investigated for active galactic nuclei (AGNs) and black hole X-ray binaries (BHXBs) from the literature. The power-law correlation index is steep ($\mu \sim$ 1.0--1.4) for radio loud
Han, Zhenhua, Liu, Xiang, Zhang, Zhen
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Lux in obscuro: Photon Orbits of Extremal Black Holes Revisited

open access: yes, 2016
It has been shown in the literature that the event horizon of an extremal asymptotically flat Reissner-Nordstrom black hole is also a stable photon sphere.
Khoo, Fech Scen, Ong, Yen Chin
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

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