Results 51 to 60 of about 3,493,414 (351)

Simulation of Binary Black Hole Spacetimes with a Harmonic Evolution Scheme [PDF]

, 2006
A numerical solution scheme for the Einstein field equations based on generalized harmonic coordinates is described, focusing on details not provided before in the literature and that are of particular relevance to the binary black hole problem.
, Arnowitt R, Ashtekar A, Babiuc M C Szilagyi B Winicour J, Baker J G Centrella J Choi D Koppitz M van Meter J Coleman Miller M, Balakrishna J, Buonanno A Cook G Pretorius F, Campanelli M Lousto C O Zlochower Y, Cook G B, Frans Pretorius, Friedrich H, Gundlachr C, Herrmann F Shoemaker D Laguna P, Lindblom L Scheel M A Kidder L E Owen R Rinne O, Nakamura T, Pretorius F, Smarr L, Thornburg J   +17 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Black Americans Receiving the COVID-19 Vaccine and Effective Strategies to Overcome Barriers: An Integrative Literature Review [PDF]

, 2022
Chad Roat, Kashica J. Webber‐Ritchey, Roxanne S. Spurlark, Young‐Me Lee   +3 more
openalex   +1 more source

Are nuclear star clusters the precursors of massive black holes? [PDF]

, 2012
We present new upper limits for black hole masses in extremely late type spiral galaxies. We confirm that this class of galaxies has black holes with masses less than 10^6 Msolar, if any.
Neumayer, Nadine, Walcher, C. Jakob
core   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Zigzag et « carré plastique » haïtiens en Amérique du nord à travers l’Autobiographie américaine de Dany Laferrière

Amerika
The « American Autobiography » by Dany Laferrière and the « Carré Plastique » by Léonel Jules, Haitian artists and friends who emigrated to Quebec, deconstruct the concept of the American city through the stylistic breaking of the rules. However, do they
Laurence Olivier-Messonnier
doaj   +1 more source

Quasinormal modes and Strong Cosmic Censorship

, 2018
The fate of Cauchy horizons, such as those found inside charged black holes, is intrinsically connected to the decay of small perturbations exterior to the event horizon.
Cardoso, Vitor, Costa, Joao L., Destounis, Kyriakos, Hintz, Peter, Jansen, Aron   +4 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Des colonies à l’Empire fasciste. La conquête de l’Afrique racontée aux enfants italiens

Strenae, 2012
In Italy, the conquest and colonization of Africa was inscribed in children’s literature as the territory occupation unfolded, in correspondence with an ideological evolution that accompanied it.
Mariella Colin
doaj   +1 more source