Results 51 to 60 of about 3,486,992 (280)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Quasinormal modes and Strong Cosmic Censorship

, 2018
The fate of Cauchy horizons, such as those found inside charged black holes, is intrinsically connected to the decay of small perturbations exterior to the event horizon.
Cardoso, Vitor, Costa, Joao L., Destounis, Kyriakos, Hintz, Peter, Jansen, Aron   +4 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Geometrothermodynamics of black holes

, 2007
The thermodynamics of black holes is reformulated within the context of the recently developed formalism of geometrothermodynamics. This reformulation is shown to be invariant with respect to Legendre transformations, and to allow several equivalent ...
C.V. Johnson, D.A. Johnston, D.A. Johnston, D.C. Brody, F. Weinhold, G. Hernández, G. Ruppeiner, G. Ruppeiner, G. Ruppeiner, G.F. Torresdel Castillo, H. Quevedo, H. Quevedo, H. Stephani, H.B. Callen, Hernando Quevedo, J. Aman, J. Aman, J. Aman, J.D. Bekenstein, J.M. Bardeen, P.C.W. Davies, R. Cai, R. Hermann, R. Mrugala, R. Mrugala, S.W. Hawking, T. Sarkar, V.I. Arnold, W. Janke, W.L. Burke   +29 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Zigzag et « carré plastique » haïtiens en Amérique du nord à travers l’Autobiographie américaine de Dany Laferrière

Amerika
The « American Autobiography » by Dany Laferrière and the « Carré Plastique » by Léonel Jules, Haitian artists and friends who emigrated to Quebec, deconstruct the concept of the American city through the stylistic breaking of the rules. However, do they
Laurence Olivier-Messonnier
doaj   +1 more source

Einstein and M{\o}ller energy-momentum complexes for a new regular black hole solution with a nonlinear electrodynamics source [PDF]

, 2016
A study about the energy and momentum distributions of a new charged regular black hole solution with a nonlinear electrodynamics source is presented. The energy and momentum are calculated using the Einstein and M{\o}ller energy-momentum complexes.
Grammenos, Th., Islam, Sayeedul, Radinschi, I., Rahaman, Farook   +3 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Des colonies à l’Empire fasciste. La conquête de l’Afrique racontée aux enfants italiens

Strenae, 2012
In Italy, the conquest and colonization of Africa was inscribed in children’s literature as the territory occupation unfolded, in correspondence with an ideological evolution that accompanied it.
Mariella Colin
doaj   +1 more source