Results 71 to 80 of about 3,493,414 (351)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Genealogy, 2020 Black boys and young men are over-represented in the youth and adult justice systems in England and Wales. Despite the Lammy Review (2017) into the treatment of and outcomes for Black, Asian, and minority ethnic individuals (BAME) in the criminal justice
Laura Robertson, John Peter Wainwright
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Identity in the Black SheepAnthology [PDF]
پژوهشنامۀ انتقادی متون و برنامههای علوم انسانی, 2018 Italian “immigration literature” is a new literary genre witch emerged in the 1990s.The stories narrated by the migrants, in its early years, talk about men and women whostarted to live a different life in a different country with or without their own ...
Mahzad Sheikholislami
doaj
Geometrothermodynamics of black holes
, 2007 The thermodynamics of black holes is reformulated within the context of the recently developed formalism of geometrothermodynamics. This reformulation is shown to be invariant with respect to Legendre transformations, and to allow several equivalent ...
C.V. Johnson +29 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Collider Production of TeV Scale Black Holes and Higher-Curvature Gravity
, 2005 We examine how the production of TeV scale black holes at colliders is influenced by the presence of Lovelock higher-curvature terms in the action of models with large extra dimensions.
+10 more
core +2 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Genealogy+CritiqueIn this article, I argue in favor of reading Black German literature as a polyphonic literary tradition, and against an isolated reading of novels, as this limits and reproduces an imagined lack of history (Geschichtslosigkeit).
Jeannette Oholi
doaj +2 more sources