Results 61 to 70 of about 3,622,310 (284)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
DATA ACQUISITION SYSTEM FOR PROSTHETIC MOTION SIMULATION
Автоматизация технологических и бизнес-процессов. The human hand, with its complex sensory capabilities, is an integral part of our daily interaction with the world. This remarkable organ contains a variety of natural sensors that enrich our experience by allowing us to perceive touch, determine ...
N. Hiulmamedov +2 more
doaj +1 more source
Express forecast of the radiation stress to the population from NPP gazoaerozol emissions NPP [PDF]
Ядерна фізика та енергетика, 2014 Express method of forecast evaluation values of dose load to the population from the territories under the simultaneous influence of radionuclide pollutants natural and artificial origin was proposed. Based on the results of radioecological research in
L. I. Grygorieva +2 more
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 2015 Seashore of Trabzon, city of in the northeastern Turkey in the Black Sea region, known as Karadeniz in Turkish, which is between Southeastern Europe and Western Asia, bounded by Europe, Anatolia and the Caucasus.135 film (36×24 ...
Gonnet-Bağana, Hatice
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The impact of stressful life events on the functionality of patients with schizophrenia
Psychiatry and Clinical Psychopharmacology, 2021 Objective: In this study, clinical symptoms, functional recovery levels and stressful life events of patients with schizophrenia were evaluated to investigate the relationship between life events and functional recovery.
Gizem Güneş +3 more
doaj
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
YOUTH ENGAGEMENT IN CIVIL SOCIETY DEVELOPMENT IN UKRAINE: PROBLEMS AND SOLUTIONS
Публічне управління та регіональний розвитокThe article outlines the ways of engaging young people in the development of civil society in Ukraine. Socially and politically active young people are one of the necessary conditions for forming a democratic society and establishing sustainable and ...
Yuliana Palagnyuk +4 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source