Results 81 to 90 of about 184,178 (309)

Construction of Borders and Walls in Contemporary Ukrainian Literature (Analysis of Oleksandr Irvanets’ and Taras Antypovych Novels)

Altre Modernità, 2021
Contemporary Ukrainian history offers fascinating cases of re-/de-bordering processes that provide evidence for how decision-makers and everyday citizens can change the historical course of the state. Border issues are particularly relevant to Ukraine, a
Alina Mozolevska, Olha Polishchuk
doaj  

Black Sea, Trabzon

, 2015
Seashore of Trabzon, city of in the northeastern Turkey in the Black Sea region, known as Karadeniz in Turkish, which is between Southeastern Europe and Western Asia, bounded by Europe, Anatolia and the Caucasus.135 film (36×24 ...
Gonnet-Bağana, Hatice
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Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A hydraulic box model study of the Mediterranean response to postglacial sea level rise. [PDF]

, 2003
This paper quantifies the role of changing sea level in affecting Mediterranean stratification using a new model of the strait-basin system, which allows for explicit time dependence.
Haines, K., Matthiesen, Stephan, Keith Haines, Haines, Keith, Stephan Matthiesen, Matthiesen, S.   +5 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The Marmara Sea Gateway since ~16 ky BP: non-catastrophic causes of paleoceanographic events in the Black Sea at 8.4 and 7.15 ky BP

, 2007
The Late Quaternary history of connection of the Black Sea to the Eastern Mediterranean has been intensely debated. Ryan, Pitman and coworkers advocate two pulses of outflow from the Black Sea to the world ocean at ~16–14.7 ky BP and ~11–10 ky BP ...
Aksu, A.E., Hiscott, R.N., Kaminski, M.A., Rochon, A., Mudie, P.J., Abrajano, T., Yaşar, D.   +6 more
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Marine algae and seagrasses of Giresun Shores (Black Sea, Turkey) [PDF]

, 2005
In this study, marine algae and sea grasses in the upper infralittoral zone of the Black Sea coast of Giresun (Black Sea, Turkey) have been examined. Totally 193 taxa have been determined.
Aysel, V., Tarakçı, B. Dural, Okudan, E. Ş., Erduğan, H.   +3 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Some considerations on the EU Danube Strategy and the Black Sea Region [PDF]

The Danube strategy can only constitute a step forward regarding the stated intentions, via the Black Sea Synergy program of the European Union towards the boosting of economic development, democratic governance, security etc., in the Black Sea region ...
Costel COROBAN
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