Results 101 to 110 of about 184,178 (309)

Interannual variability of the early summer coccolithophore blooms in the Black Sea: impacts of climatic factors

open access: yes, 2003
Interannual variability of the early summer (May-June) coccolithophore blooms within surface waters of the Black Sea was studied by means of satellite-based bio-optical observations. The performance of two coccolithophore detection algorithms were tested
Kubilay, N, Cokacar, T, Oguz, T
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

A study on dynamic modeling to examine the impact of reducing water pollution on market condition in the Turkish Black Sea Basin [PDF]

open access: yes
The Black Sea has severe water pollution problems during the last three decades due to tremendous loads of different types of pollutants discharged from the entire basin Therefore, finding solutions to improve the environmental status of the Black Sea is
Ulger Suleyman, Higano Yoshiro
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Nitrogen Problem for the Black Sea Ecosystem

open access: yes, 2013
The aim of the report presented was development of a comprehensive scheme of balance and biogeochemical N cycling for the Black Sea: discussion of exchange of N, its main sources/sinks and the processes involved: identify weak under-studied points and ...
Medinets, Sergiy V.
core  

Geopolitical Issues in the Current Crisis Between Ukraine and Russia

open access: yes, 2015
This article concentrates on the new geopolitical role and place of Ukraine, taking into account consequences of the military conflict with Russia.
GIRGIN, Dogan
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Pleistocene Sea Levels possibly indicated by Buried Black Sediments in the Black Sea [PDF]

open access: yesNature, 1970
MODERN surface sediments containing H2S are often coloured black by fine grained, iron monosulphide minerals such as mackinawite, Fe1+xS, and greigite, Fe3S4. The black monosulphides are thermodynamically unstable, under H2S-rich sedimentary conditions, relative to the disulphide pyrite, FeS21,2, which is not a black pigmenting agent.
openaire   +2 more sources

Socio-Economics of the Black Sea Coast

open access: yes, 2019
This chapter focused on the reviewing of socio-economic drivers (sectors directly or indirectly related to the Black Sea) as well as on the pressure on the environment, social and economic consequences of environmental changes, and riparian countries ...
Karamushka, Victor, Bon, Oleksandr
core  

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