Results 91 to 100 of about 184,178 (309)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Main Aspects of the Georgia`s Energy Policy and Energy Independence
, 2015 In the research, there are analyzed the main political and economic benefits for Georgia from the realization of Southern Corridor - TANAP and TAP projects in the short-term and long-term perspectives, possibilities of the strengthening cooperation ...
CHITADZE, Nika
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The contrasting oceanography of the Rhodes Gyre and the Central Black Sea
, 2006 The Rhodes Gyre, a prominent feature of the oceanography of the eastern Mediterranean, is modelled as a vertical, continuous flow, cylindrical reactor illuminated during the day at its upper end. If the Gyre is supposed to be in a steady state whilst the
Davie, Alexander M. +11 more
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
The Dynamics of Black Sea Subregionalism
, 2012 Conflict and cooperation are two dynamics that have shaped the political economy and international relations around the Black Sea since the early nineties.
Manoli, Panagiota
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Bioactive phytosterols and fatty acids profile of traditional foods from black sea area countries [PDF]
, 2011 Phytosterols (PS) are abundant in foods of plant origin and vegetable oils. These compounds have received particular attention due to their capability to lower serum cholesterol levels, resulting in significant reduction of the risk of heart disease ...
Sanches-Silva, A. +5 more
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
CRIBWORK IN THE BLACK SEA. (ABSTRACT). [PDF]
Minutes of the Proceedings of the Institution of Civil Engineers, 1875 n ...
openaire +1 more source