Results 71 to 80 of about 103,616 (268)
Transfer of royal fish and the non-evolutionary history of Black Sea sturgeons
Academia BiologyThe evolutionary relationship between Caspian and Black Sea sturgeons has long attracted scholarly attention. Although the two basins have been hydrologically isolated for at least 5000 years, genetic studies reveal the presence of Black Sea ...
Gigi Tevzadze
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Prospects for an EU Macro-Regional Approach in the Black Sea Area
PlaNext, 2016 Recent years have witnessed the emergence of the first EU macro-regional strategies as a new instrument for territorial governance. This paper argues that both the benefits and limitations of the macro-regional approach are largely determined by the ...
Galya Vladova, Jörg Knieling
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Is the exchange between the Black Sea and the Mediterranean changing over time?
Environmental Research CommunicationsThe Black Sea Waters (BSW) that are exported into the Aegean Sea largely control its overturning circulation, as well as its regional biogeochemical characteristics.
I G Mamoutos +6 more
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Prospects for an EU macro-regional approach in the Black Sea region
PlaNext, 2016 Recent years have witnessed the emergence of the first EU macro-regional strategies as a new instrument for territorial governance. This paper argues that both the benefits and limitations of the macro-regional approach are largely determined by the ...
Galya Vladova, Jörg Knieling
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Journal of Marine Science and EngineeringMicroplastics (
Andreea-Mădălina Ciucă +2 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source