Results 81 to 90 of about 103,616 (268)

PRELIMINARY RESULTS OF GEO-ARCHAEOLOGICAL RESEARCH OBTAINED DURING THE 3rd INTERNATIONAL EXPEDITION OF THE R/V “MARE NIGRUM” (01.06.2024 – 15.06.2024)

Геологія і корисні копалини Світового океану
The research cruise was carried out within the framework of the Horizon 2020 project “Development of Optimal and Open Research Support for the Black Sea” (DOORS). The DOORS-3 program was developed as part of Work Package 4. The project started on June 1,
M.M. Ievlev, O.V. Chubenko, V.O. Iemelianov, N.O. Fedoronchuk   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Russian Geographical Studies of the Black Sea Region in 1800s - Early 1850s

RUDN Journal of Russian History
The authors in their article reveals the key areas and results of geographical research of the Black Sea region in the 1800s - early 1850s. Based on archival materials and historical and geographical research, the authors illustrate that this stage of ...
Yuri Y. Ierusalimskiy, Svetlana Y. Ierusalimskaya, Stanislav F. Amanov   +2 more
doaj   +1 more source

Geothermal sections of the earth's crust and upper mantle of the Black Sea and its northern border

Геофизический журнал, 2011
Results of measurements of heat flow and mathematical simulation of geothermic state of the lithosphere along two profiles, crossing the western and the eastern depressions of the Black Sea and flanking northward tectonic structures of different age have
R.I. Kutas
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

DISTRIBUTED MARITIME DENIAL: DRONE WARFARE IN THE BLACK SEA AND NATO ADAPTATION IN SEMI-ENCLOSED SEAS

Studia Universitatis Babeş-Bolyai. Studia Europaea
This article examines how drone warfare in the Black Sea has reshaped the logic of maritime denial in semi-enclosed and constrained seas, and what lessons NATO should draw from Ukraine’s experience.
Raluca MOLDOVAN, Valentin NAUMESCU
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Introduction

Revista Română pentru Studii Baltice şi Nordice, 2009
I hope that the novelty of interpretation and the new findings behind the articles included in the first issue of RRSBN will attract scholarly and public interest and give birth to fresh academic debates on the exchange of cultural values between the ...
Silviu Miloiu
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Editorial Foreword [PDF]

Revista Română pentru Studii Baltice şi Nordice, 2013
A large part of the articles published in the current issue of Revista Română de Studii Baltice şi Nordice / The Romanian Journal for Baltic and Nordic Studies have been initially presented at the Fourth International Conference on Baltic and Nordic ...
Silviu Miloiu
doaj