Results 81 to 90 of about 2,866,338 (297)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
, 2015 Mergers of gas-rich galaxies are key events in the hierarchical built-up of cosmic structures, and can lead to the formation of massive black hole binaries.
Colpi, Monica +3 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Black hole collisions: how far can perturbation theory go? [PDF]
, 1999 The computation of gravitational radiation generated by the coalescence of inspiralling binary black holes is nowdays one of the main goals of numerical relativity.
Campanelli, Manuela
core +2 more sources
Non-equilibrium condensation process in holographic superconductor with nonlinear electrodynamics
, 2016 We study the non-equilibrium condensation process in a holographic superconductor with nonlinear corrections to the U(1) gauge field. We start with an asymptotic Anti-de-Sitter(AdS) black hole against a complex scalar perturbation at the initial time ...
Gong, Yungui, Liu, Yunqi, Wang, Bin
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Energies, 2017 The black start capability is vital for microgrids, which can potentially improve the reliability of the power grid. This paper proposes a black start strategy for microgrids based on a parallel restoration strategy.
Jing Wang +3 more
doaj +1 more source
Dynamical behaviour of the `beads' along the magnetic field lines near a rotating black hole
, 2010 The elements of the cold magnetic driven flows behave like beads on the magnetic field line. The inclination of the field lines at the surface of the disc plays a crucial role on the nature of the magnetically driven outflow.
Cao, Xinwu
core +1 more source