Results 51 to 60 of about 16,222,725 (302)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Religions, 2019 In this essay, we will explore the variances in Madea’s character and presence on stage and on screen in both productions of Tyler Perry’s Madea Goes to Jail: The Play and Madea Goes to Jail.
Katherine Whitfield, Andre E. Johnson
doaj +1 more source
Terry M. Black to the Jacksons
, 1966 Terry M. Black, writing from Camp Pendleton, California, to his parents, the Jacksons, in Van Buren, Arkansas, discusses his feelings about his recent leave in Van Buren, the current plans for his unit's deployment, and some of the training and duty he ...
Black, Terry Moore, 1946-2022;
core
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Asian Review of Political EconomyThe recent events in the Middle East caught most political commentators, observers and thinkers by surprise. Who would have imagined that a non-state actor like Hamas could launch an attack on Israel and create such a complex condition for a powerful ...
Seevan Saeed
doaj +1 more source
Terry M. Black, MCRD, to the Jacksons
, 1964 Terry M. Black, writing from the MCRD (Marine Corps Recruiting Depot), San Diego, California, to his parents in Van Buren, Arkansas, talks about his 50th day of training, and the time he has left in training.
Black, Terry Moore, 1946-2022;
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Black Studies @ Eastern Illinois University
, 2023 One of a series of volumes that document campus histories of Black Studies programs. After the first four volumes produced by students in 2010, a number of additional volumes have been created by students taking a Fall 2022 course at the University of ...
Burkins, Camryn, Alkalimat, Abdul
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source