Results 51 to 60 of about 2,005,603 (264)

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Decolonial Embodiments: Materiality, Disability, and Black Being in Djaimilia Pereira de Almeida’s Luanda, Lisboa, Paraíso

Humanities
Grounded in, and in dialogue with, Djaimilia Pereira de Almeida’s Luanda, Lisboa, Paraíso of 2018, this paper interrogates a particular time and place of coloniality and racial capital’s reproduction of Black fungibility in late twentieth-century ...
Daniel F. Silva
doaj   +1 more source

The Right are back to Power [PDF]

Научно-аналитический вестник Института Европы РАН, 2019
In early July, in the course of the extraordinary parliamentary elections in Greece, the center-right New Democracy Party, led by Kyriakos Mitsotakis, won a convincing victory. Elections took place after the leftist radical SYRIZA party of Prime Minister
Serhey Zabelin
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Review of "Black Gathering: Art, Ecology, Ungiven Life" by Sarah Jane Cervenak (Duke University Press)

Lateral
In Black Gathering: Art, Ecology, Ungiven Life, Sarah-Jane Cervenak engages with the ecoaesthetic, ecopoetic, and ecoliterary work of Black artists and writers who, through their engagement with the environment, imagine the earth and Black life outside ...
Kelann Currie-Williams
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Tyler Perry and the Rhetoric of Madea: Contrasting Performances of Perry’s Leading Lady as She Appears on Stage and Screen

Religions, 2019
In this essay, we will explore the variances in Madea’s character and presence on stage and on screen in both productions of Tyler Perry’s Madea Goes to Jail: The Play and Madea Goes to Jail.
Katherine Whitfield, Andre E. Johnson
doaj   +1 more source

Black Unsettlement: Embodied Blackness and Black Studies in the Irish Context

Irish Journal of Sociology
Reflecting the call for diverse opinions in knowledge production, this article is a personal perspective on the positioning of Black Studies in Ireland. Black Studies as praxi-theory foregrounds the inseparability of embodied experiences from epistemic subject, since the knowledge production process is inherently subjective.
openaire   +2 more sources