Results 71 to 80 of about 2,005,603 (264)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Blackness and the Sociality of Sports: A Conversation with Fred Moten
LateralUsing the management of Black athlete protest (e.g., Colin Kaepernick, Naomi Osaka, LeBron James, Brittney Griner) in the post-Ferguson era as a foil, Fred Moten, Roberto Sirvent, and Charles Athanasopoulos engage in a critical conversation surrounding ...
Roberto Sirvent +2 more
doaj +1 more source
Parse Journal, 2023 This song is silent. It is written in many voices. Sourced from fugitivity existing on a lower frequency. Silently, it sings alongside inaudible tunes, tuning to, tuning with, knowing otherwise. Quiet search for materiality through the unseen and silent,
Marie-Louise Richards
doaj
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Cryptojewish Speculations for a Black Planetary
LateralA movement is growing to reimagine jewishness in a decolonial frame. As zionism loses its grip over white and white-passing jews in the global north, and with increasing momentum after Israel’s genocidal reprisal following the events of October 2023, the
Ben Spatz
doaj +1 more source
Abkhazia in 2014—2017 (The Internal Political Crisis Dynamics)
Международная аналитика, 2018 The article explores the political crisis in Abkhazia in 2014 -2017. The author analyzes its visible preconditions, as well as the reasons that are beyond the political situation (nation building, Abkhazian society’s attitude to sovereignty, the ...
V. Novikov
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Prissy’s Quittin’ Time: The Black Camp Aesthetics of Kara Walker
Open Cultural Studies, 2017 Through a close reading of Walker’s first silhouette instalment-the audaciously titled Gone, An Historical Romance of a Civil War as it Occurred Between the Dusky Thighs of One Young Negress and Her Heart (1994)-this article examines how Walker utilises ...
Stephens Brian
doaj +1 more source
Abkhazia – 2018: The Dynamics of Domestic Political Process in the Prospect of Presidential Election
Международная аналитика, 2019 The paper considers the dynamics of the domestic political process in the Republic of Abkhazia in 2018. The pivot of this process was the presidential election campaign that started in 2018.
Vladimir Novikov
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source