Results 101 to 110 of about 93,413 (314)
Am I Still Too Black For You?: Schooling and Secular Change in Skin Tone Effects [PDF]
Analysts disagree about whether the Civil Rights/Black Power eras lessened the influence of skin tone on education. The paper finds that, holding family background constant, the educational disadvantages of dark and very dark blacks persisted between ...
Linda Datcher Loury
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Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Racial Difference in the Relationship Between Health and Happiness in the United States
Sharon Cobb,1 Arash Javanbakht,2 Ebrahim Khalifeh Soltani,3 Mohsen Bazargan,4,5 Shervin Assari4 1School of Nursing, Charles R Drew University of Medicine and Science, Los Angeles, CA, USA; 2Department of Psychiatry and Behavioral Neurosciences, Wayne ...
Cobb S +4 more
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Racial Discrimination - risk factor for high blood pressure? a survey study
The importance of institutional health practices as representative or not of institutional racism in the treatment of the hypertensive client was object of this study.
Isabel CF da Cruz
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Long-Run Convergence of Ethnic Skill Differentials [PDF]
This paper investigates if the ethnic skill differentials introduced into the United States by the inflow of very dissimilar immigrant groups during the Great Migration of 1880-1910 disappeared during the past century.
George J. Borjas
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Take the money and run: Economic segregation in U.S. metropolitan areas [PDF]
Compared to racial segregation, economic segregation has received little attention in recent empirical literature. Yet a heated debate has arisen concerning Wilson's hypothesis (1987) that increasing economic segregation plays a role in the formation of ...
P. A. Jargowsky
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Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
The effects of Obama's political success on the self-rated health of Blacks, Hispanics, and Whites [PDF]
Stress in the social environment can affect individual health. Election of the first Black President of the United States provides an opportunity to assess how a positive change in the macro-political climate impacts the health of Americans.
Timberlake, Jeffrey +2 more
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