Results 81 to 90 of about 108,735 (304)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
, 1972 black n. . . it is common to refer to the Protestants as "blacks" and the Roman Catholics as "micks." These phrases may be used in two ways: (1) jokingly, without meaning insult (2) but if it is said seriously it is regarded by both (the ...
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Increased Metabolic Burden Among Blacks: A Putative Mechanism for Disparate COVID-19 Outcomes
Diabetes, Metabolic Syndrome and Obesity, 2020 Girardin Jean-Louis,1 Arlener D Turner,1 Peng Jin,2 Mengling Liu,2 Carla Boutin-Foster,3 Samy I McFarlane,3 Azizi Seixas1 1Departments of Population Health, Psychiatry, and Biostatistics, New York University Langone Health, New York, NY, USA; 2Department
Jean-Louis G +6 more
doaj
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Who Goes to College? Differential Enrollment by Race and Family Background [PDF]
While trends in college enrollment for blacks and whites have been the subject of study for a number of years, little attention has been paid to the variation in college enrollment by socioeconomic status (SES).
Amir Sufi, Sandra E. Black
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Frontiers in Psychiatry, 2016 Background: The Center for Epidemiologic Studies Depression (CES-D) scale is one of the most widely used tools to measure depressive symptoms in epidemiological studies.
Shervin Assari +2 more
doaj +1 more source
The Complexion Gap: The Economic Consequences of Color among Free African Americans in the Rural Antebellum South [PDF]
Historians of U.S. race relations typically portray southern whites as reluctant to recognize or act favorably upon complexion-based differences within the African American community.
Howard Bodenhorn
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