Results 61 to 70 of about 90,637 (266)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
The History of Blacks in Canada A Selectively Annotated Bibliography
This fascinating bibliography of source materials clearly demonstrates the significant roles blacks have played in the history and culture of Canada from its beginnings as well as their 400-year fight for equity and justice. Organized by area of endeavor
Junne, George H.
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, 2013 Loren Lipworth,1 Sergio Fazio,1,2 Edmond K Kabagambe,1 Heather M Munro,3 Victor C Nwazue,1 Robert E Tarone,3 Joseph K McLaughlin,3 William J Blot,1,3 Uchechukwu KA Sampson1,2,41Department of Medicine, Vanderbilt University Medical Center, 2Department of ...
Munro HM +8 more
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Schooling and the Great Migration [PDF]
In 1900, 90 percent of America?s black population lived in the South and only 4.3 percent of those born in the region era living elsewhere. By 1950 the proportion of blacks living in the South had declined to 68 percent and 19.6 percent of those born in ...
Robert A. Margo
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FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Medicaid: A Lifeline for Blacks and Latinos with Serious Health Care Needs
, 2011 Report, commissioned by the Families USA, the Joint Center Health Policy Institute and other allies, describes the likely impact on African Americans and Latinos of cuts to Medicaid, the program on which millions of low-income Americans rely. It contains
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