Results 171 to 180 of about 942,071 (291)

Bladder Carcinoma [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1960
openaire   +2 more sources

Tumor‐Derived Exosomal TAGLN2 Promotes Metastasis by Inducing Vascular Permeability and Angiogenesis via the NRP1/SEMA4D/YAP Axis

open access: yesAdvanced Science, EarlyView.
Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu   +7 more
wiley   +1 more source

m5C‐Modified tRF3b‐CysGCA‐23 Suppresses Bladder Cancer Malignancy by Repressing H3K18 Lactylation via Stabilizing RBM4

open access: yesAdvanced Science, EarlyView.
In this study, we identified an NSUN6‐dependent m5C‐modified tsRNA, m5C‐tRF3b CysGCA‐23 (mtRC), that is downregulated in BC and inversely correlated with disease progression. Mechanistically, mtRC suppresses BC malignancy by stabilizing RBM4, attenuating glycolysis, and thereby limiting H3K18 lactylation–mediated activation of IL1RAP and VASH2 ...
Xiaoling Ying   +16 more
wiley   +1 more source

Two cases of emphysematous cystitis with urinary bladder rupture. [PDF]

open access: yesOxf Med Case Reports
Ngo XT   +11 more
europepmc   +1 more source

KMT2C Loss Promotes NF2‐Wildtype Meningioma Progression and Ferroptosis Sensitivity via Epigenetic Repression of Hippo Signaling

open access: yesAdvanced Science, EarlyView.
In NF2–wild‐type meningiomas, loss of the epigenetic regulator KMT2C suppresses NF2 transcription and inactivates Hippo signaling, driving tumor progression and increasing ferroptosis sensitivity. Restoration of histone acetylation reverses these effects and inhibits tumor growth, identifying KMT2C as a key regulator linking epigenetic control, NF2 ...
Liuchao Zhang   +13 more
wiley   +1 more source

Response to the Letter to the Editor Entitled “Revisiting Vincristine for FSGS: Proof-of-Mechanism Arrives, but Whom Should we Treat?”

open access: yesKidney International Reports
William J. Mason   +11 more
doaj   +1 more source

Bladder Cancer [PDF]

open access: yesCA: A Cancer Journal for Clinicians, 1978
openaire   +2 more sources

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

open access: yesAdvanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma   +16 more
wiley   +1 more source

Bladder Preservation with Concurrent Chemoradiotherapy Following Complete Response to Induction Systemic Therapy in Patients with Muscle-Invasive Bladder Cancer: A Review of the Existing Literature. [PDF]

open access: yesCancers (Basel)
Ntoumas GN   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy