Results 41 to 50 of about 1,313,120 (353)

Epidemiology of Bladder Cancer

Medical Science, 2020
Based on the latest GLOBOCAN data, bladder cancer accounts for 3% of global cancer diagnoses and is especially prevalent in the developed world. In the United States, bladder cancer is the sixth most incident neoplasm.
Kalyan Saginala, Adam Barsouk, J. Aluru, Prashanth Rawla, S. Padala, Alexander Barsouk   +5 more
semanticscholar   +1 more source

The role of the HIF‐1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer

Cancer Communications, 2021
As a rate‐limiting enzyme of glycolysis, pyruvate kinase muscle isozyme M2 (PKM2) participates in tumor metabolism and growth. The regulatory network of PKM2 in cancer is complex and has not been fully studied in bladder cancer. The 5‐methylcytidine (m5C)
Jing-zi Wang, Wei Zhu, Jie Han, X. Yang, R. Zhou, Hongcheng Lu, Hao Yu, Wenbo Yuan, Pengchao Li, J. Tao, Q. Lu, Jifu Wei, Haiwei Yang   +12 more
semanticscholar   +1 more source

Outcome of renal grafts after simultaneous kidney/ pancreas transplantation [PDF]

, 1991
Nineteen patients with endstage renal failure due to Type 1 (insulin-dependent) diabetes mellitus received simultaneous pancreas/kidney transplants using bladder drainage technique.
D. Abendroth, G. Hillebrand, H. Schneeberger, I. Petry, LA Castro, O Hillebrand, R. Landgraf, S. Schleibner, SJ Knechtle, W. -D. Illner, W. Land   +10 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Understanding Urogenital Schistosomiasis-Related Bladder Cancer: An Update

Frontiers in Medicine, 2018
Infection with Schistosoma haematobium leads to urogenital schistosomiasis, which has been correlated with the occurrence of bladder cancer. However, mechanisms responsible for this association have not yet been clearly identified.
Kenji Ishida, Michael H. Hsieh, Michael H. Hsieh, Michael H. Hsieh   +3 more
doaj   +1 more source

Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial.

The Lancet Oncology, 2020
BACKGROUND BCG is the most effective therapy for high-risk non-muscle-invasive bladder cancer. Nadofaragene firadenovec (also known as rAd-IFNa/Syn3) is a replication-deficient recombinant adenovirus that delivers human interferon alfa-2b cDNA into the ...
S. Boorjian, M. Alemozaffar, B. Konety, N. Shore, L. Gomella, A. Kamat, T. Bivalacqua, J. Montgomery, S. Lerner, J. E. Busby, M. Poch, P. Crispen, G. Steinberg, A. Schuckman, T. Downs, R. Svatek, Joseph W. Mashni, B. Lane, T. Guzzo, G. Bratslavsky, L. Karsh, M. Woods, Gordon Brown, D. Canter, A. Luchey, Y. Lotan, T. Krupski, B. Inman, Michael Williams, Michael Cookson, K. Keegan, G. Andriole, A. Sankin, A. Boyd, M. O'Donnell, D. Sawutz, Richard Philipson, R. Coll, V. Narayan, F. Treasure, S. Yla-Herttuala, Nigel R. Parker, C. Dinney   +42 more
semanticscholar   +1 more source

Multiparametric MRI of the bladder: inter-observer agreement and accuracy with the Vesical Imaging-Reporting and Data System (VI-RADS) at a single reference center [PDF]

, 2019
Objectives: To evaluate accuracy and inter-observer variability using Vesical Imaging-Reporting and Data System (VI-RADS) for discrimination between non-muscle invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC).
Barchetti, Giovanni, Buccilli, Dorelsa, Campa, Riccardo, Catalano, Carlo, Catto, James W. F., Ceravolo, Isabella, De Berardinis, Ettore, Del Giudice, Francesco, Gallucci, Michele, Panebianco, Valeria, Salvo, Vincenzo, Simone, Giuseppe   +11 more
core   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

A clinical microscopy dataset to develop a deep learning diagnostic test for urinary tract infection

Scientific Data
Urinary tract infection (UTI) is a common disorder. Its diagnosis can be made by microscopic examination of voided urine for markers of infection. This manual technique is technically difficult, time-consuming and prone to inter-observer errors.
Natasha Liou, Trina De, Adrian Urbanski, Catherine Chieng, Qingyang Kong, Anna L. David, Rajvinder Khasriya, Artur Yakimovich, Harry Horsley   +8 more
doaj   +1 more source

The Value of Negative Urinary Dipstick Tests for Haematuria in Patients Undergoing Surveillance for Low-grade Ta Urothelial Cancer: A Two-stage Prospective Clinical Study in 524 Patients

European Urology Open Science
Background and objective: The risk of first recurrence beyond 5 yr for patients with low-grade (LG) Ta non–muscle-invasive bladder cancer (NMIBC) is low enough to consider discontinuing cystoscopic surveillance at that point.
Chandrarajan Premal Shah, Tanya Lord-McKenzie, Antonios Makris, Matthew Trail, Jennifer Gray, Gordon Smith, Paramananthan Mariappan   +6 more
doaj   +1 more source