Results 21 to 30 of about 618,549 (318)

Therapeutic effect of adipose-derived regenerative cells on bladder function in rats with underactive bladder [PDF]

, 2020
2020-08We examined the effect of adipose-derived regenerative cells (ADRC) on bladder functions in a rat model of detrusor underactivity (DU) induced by bladder over-distention.
Takai, Shun, Majima, Tsuyoshi, Yamamoto, Tokunori, Gotoh, Momokazu, Funahashi, Yasuhito, Mori, Aya, Matsukawa, Yoshihisa   +6 more
core   +1 more source

Patient and Healthcare Professional Perspectives from ESMO 2022 on Bladder and Kidney Cancer: A Podcast

Oncology and Therapy, 2023
In this plain language podcast, highlights from the European Society for Medical Oncology (ESMO) Congress are discussed for a second year in a row, from the perspective of both a patient advocate and a healthcare professional.
Alex Filicevas, Thomas Powles
doaj   +1 more source

Human urinary exosomes in bladder cancer patients : properties, concentrations and possible clinical application

, 2015
OBJECTIVE: High grade bladder cancer is extremely aggressive. Early detection is thus an important challenge. De- velopment of non-invasive diagnostic tools particularly using urine samples could be of importance in the diagnosis and surveillance of ...
Mullen, Peter, Chapman, Alex, Hacker, Christian, Leung, Steve, Lucocq, John Milton, Bowness, James Simeon, McLornan, Liz, Cameron, Ruth, Harrison, David James, Powis, Simon John, Chinn, David John, Riches, Andrew Clive   +11 more
core   +1 more source

A prospective observational study of urinary cytokines and inflammatory response in patients with Overactive Bladder Syndrome

BMC Urology, 2021
Background Contemporary studies have discredited the methods used to exclude urinary tract infection (UTI) when treating overactive bladder (OAB). Thus we must revisit the OAB phenotype to check that UTI has not been overlooked.
Kiren Gill, Harry Horsley, Sheela Swamy, Rajvinder Khasriya, James Malone-Lee   +4 more
doaj   +1 more source

Diagnostic Role and Clinical Impact of Zr-Girentuximab PET-CT for the Diagnosis and Treatment of Clear-Cell Renal Cell Carcinoma

Diagnostics
Background/Objectives: Clear-cell renal cell carcinoma (ccRCC) represents the predominant histologic subtype of renal cancer and poses persistent diagnostic challenges, particularly in the evaluation of small renal masses, where conventional imaging and ...
Daniel A. González-Padilla, Felipe Villacampa-Auba, Jorge Caño-Velasco, José Daniel Subiela, María Rodríguez, Carlos Yánez, Andrés Calva, Vanessa Talavera, Carmina Muñoz, Marcos Torres, Guillermo Barbas, Guillermo Andrés, Daniel Sánchez-Zalabardo, Edgar Fernando Guillén-Valderrama, Bernardino Miñana-López   +14 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Professional perspectives on impacts, benefits and disadvantages of changes made to community continence services during the COVID-19 pandemic: findings from the EPICCC-19 national survey

BMC Health Services Research, 2022
Background The COVID-19 pandemic required changes to the organisation and delivery of NHS community continence services which assess and treat adults and children experiencing bladder and bowel difficulties.
Cecily Palmer, Davina Richardson, Juliette Rayner, Marcus J. Drake, Nikki Cotterill   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

A clinical microscopy dataset to develop a deep learning diagnostic test for urinary tract infection

Scientific Data
Urinary tract infection (UTI) is a common disorder. Its diagnosis can be made by microscopic examination of voided urine for markers of infection. This manual technique is technically difficult, time-consuming and prone to inter-observer errors.
Natasha Liou, Trina De, Adrian Urbanski, Catherine Chieng, Qingyang Kong, Anna L. David, Rajvinder Khasriya, Artur Yakimovich, Harry Horsley   +8 more
doaj   +1 more source

Understanding Urogenital Schistosomiasis-Related Bladder Cancer: An Update

Frontiers in Medicine, 2018
Infection with Schistosoma haematobium leads to urogenital schistosomiasis, which has been correlated with the occurrence of bladder cancer. However, mechanisms responsible for this association have not yet been clearly identified.
Kenji Ishida, Michael H. Hsieh, Michael H. Hsieh, Michael H. Hsieh   +3 more
doaj   +1 more source