Results 201 to 210 of about 844,682 (297)

Cardiovascular Disease, Functional Disability, and QoL as Associated Factors With Urinary Incontinence in Older Individuals—Cross‐Sectional Study

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Urinary incontinence (UI) is highly prevalent among older adults and is associated with functional decline and reduced quality of life (QoL). This study estimated the prevalence of UI and investigated factors independently associated with UI among community‐dwelling older adults in São Paulo, Brazil.
José Tadeu Nunes Tamanini   +6 more
wiley   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

Functional MRI Analysis of Brain Activity in Rats With Diabetic Bladder Dysfunction. [PDF]

open access: yesCNS Neurosci Ther
Li M   +7 more
europepmc   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell–Derived Exosomes Attenuate Renal Fibrosis by Suppressing Fibroblast Activation via the INHBA/PI3K/AKT Pathway

open access: yesPediatric Discovery, EarlyView.
MSC‐Exo derived from human umbilical cord (HucMSC‐Exo) downregulates INHBA expression, consequently modulating the PI3K/AKT signaling cascade. This regulation attenuates renal fibroblast activation and extracellular matrix deposition, thereby exerting a renoprotective effect against fibrosis.
Meiling Chen   +11 more
wiley   +1 more source

Adenosine Receptor Mechanisms Underlying Bladder Dysfunction in Male Rats With Bladder Outlet Obstruction. [PDF]

open access: yesNeurourol Urodyn
Takaoka EI   +7 more
europepmc   +1 more source

Proteomic Analysis of Mixed Cell Membrane Extracts From Triple‐Negative Breast Cancer Cell Lines Revealed Broad Metabolic Reprogramming Associated With Tumor Progression

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca   +7 more
wiley   +1 more source

Hypovitaminosis D in acute inpatient cancer rehabilitation: Prevalence, predictors, and practical implications

open access: yesPM&R, EarlyView.
Abstract Background Hypovitaminosis D is associated with adverse health outcomes, including increased mortality in patients with cancer. Although vitamin D insufficiency (23%–72%) and deficiency (20%–71%) are common among patients admitted to inpatient rehabilitation, their prevalence and predictors in cancer‐specific inpatient rehabilitation ...
Jegy M. Tennison   +7 more
wiley   +1 more source

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