Results 211 to 220 of about 844,682 (297)

A catheter-associated urinary tract infection mouse model to study bladder dysfunction and pain. [PDF]

Pain
Schillebeeckx L, Caldwell A, Luyten K, Sliwinska M, Gevaert T, Everaerts W, Voets T.   +6 more
europepmc   +1 more source

Expert consensus on clinical trial design guidelines for FLASH radiotherapy

Precision Radiation Oncology, EarlyView.
• FLASH radiotherapy has emerged as a transformative technology due to the underlying FLASH effect. • As FLASH radiotherapy moves toward clinical application, establishing standardized trial design principles is critical. • This expert consensus provides a roadmap for rigorous clinical evaluation of FLASH radiotherapy, accelerating safe translation of ...
Hui Luo, Chen Cheng, Chengliang Yang, Bing Li, Jiandong Zhang, Jinbo Yue, Zhaoyang Lou, Hui Liu, Jing Cai, Hong Ge   +9 more
wiley   +1 more source

The RAGE Inhibitor TTP488 (Azeliragon) Improves Diabetic Bladder Dysfunction in Leptin-Deficient Obese Mice. [PDF]

Antioxidants (Basel)
Oliveira AL, Medeiros ML, Campos ATP, Cesar CL, Mónica FZ, Antunes E.   +5 more
europepmc   +1 more source

Urinary Soluble Collagen Levels Are Associated With Moderate/Severe LUTS

The Prostate, EarlyView.
ABSTRACT Background Expansion of the stromal compartment of the prostate concurrent with fibroblast activation and increased collagenization is now recognized as a pathobiology likely contributing to Lower Urinary Tract Symptoms (LUTS). However, approaches to quantitatively and, ideally, non‐invasively, assess prostatic collagenization in vivo are not ...
Marissa Sarna‐McCarthy, Claweens Quetant, Quentin D'Arcy, Richard Caesar, Kourosh Zarringhalam, Jill A. Macoska   +5 more
wiley   +1 more source

Astragalus Polysaccharides Ameliorate Diabetic Bladder Dysfunction via Normalization of Neuromuscular Conduction. [PDF]

J Agric Food Chem
Liang S, Xu S, Ye S, Liang L, Li H, Liu J, Zhang Y, Zou F, Liang X, Tan B, Cao H.   +10 more
europepmc   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Assessments of neurogenic bladder dysfunction induced by spinal cord injury, bladder outlet obstruction and diabetes: a comparative study of rat models. [PDF]

Transl Androl Urol
Sun S, Zhang J, Ainiwaer A, Liu Y, Shen D, Jiang Y, Chen H, Bohetiyaer A, Wu T, Gao Y, Li W, Xu Y, Xu T, Yan Y.   +13 more
europepmc   +1 more source

Baicalin Induces Ferroptosis in Breast Cancer Through a Novel STAT3/HO‐1/GPX4 Regulatory Axis

Phytotherapy Research, EarlyView.
BA inhibits STAT3 phosphorylation and activation in BC cells, accompanied by decreased expression of HO‐1 and GPX4. Reduced GPX4 activity impairs lipid peroxide clearance, promoting ROS accumulation and lipid peroxidation, which ultimately triggers ferroptosis and inhibits cell proliferation.
Tingting Guo, Fansu Meng, Detang Li, Maciej Mazur, Alicia Marcelina Díaz García, Mulazim Hussain Asim, Zhong Chen, Yiqi Chen, Yixuan Lin, Zhenjiang Yang, Panpan Wang, Yu Cai   +11 more
wiley   +1 more source

Targeting NADPH Oxidase as an Approach for Diabetic Bladder Dysfunction. [PDF]

Antioxidants (Basel)
Silveira THR, Silva FH, Hill WG, Antunes E, de Oliveira MG.   +4 more
europepmc   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source