Results 41 to 50 of about 201,032 (307)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Neural-Network-Based Prediction of Non-Burial Overwintering Material Covering Height for Wine Grapes

open access: yesAgronomy
Grapevines in cold regions are prone to frost damage in winter. Due to its adverse effects on soil structure, plant damage, high operational costs, and limited mechanization feasibility, buried soil overwintering has been gradually replaced by no-burial ...
Yunlong Ma   +4 more
doaj   +1 more source

The effect of blanket system and port plugs on the harmonic components of error field and optimizing approach investigation

open access: yesNuclear Fusion, 2023
The fusion plasma is sensitive to the penetration of the toroidal mode numbers $n$ harmonic components of the error fields (EFs), and the toroidal mode components of the EFs are closely tied to the toroidal distribution of the magnetic field source.
Zhao Liu   +3 more
doaj   +1 more source

Aerogel Blanket Insulation Materials for Cryogenic Applications [PDF]

open access: yes, 2009
Aerogel blanket materials for use in thermal insulation systems are now commercially available and implemented by industry. Prototype aerogel blanket materials were presented at the Cryogenic Engineering Conference in 1997 and by 2004 had progressed to ...
Augustynowicz, S.   +4 more
core   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

The effect of Li2TiO3 pebbles on the mechanical properties of ARAA under breeding blanket conditions

open access: yesNuclear Materials and Energy
The breeding blanket serves as a critical element for achieving a self-sustaining tritium cycle and generating sufficient energy in fusion reactors.
Yunsong Jung   +4 more
doaj   +1 more source

Molecular Dynamics Simulations of Lead and Lithium in Liquid Phase [PDF]

open access: yes, 2011
Pb17Li is today a reference breeder material in diverse fusion R&D programs worldwide. Extracting dynamic and structural properties of liquid LiPb mixtures via molecular dynamics simulations, represent a crucial step for multiscale modeling efforts ...
Cuesta Lopez, Santiago   +2 more
core   +3 more sources

ITER solid breeder blanket materials database [PDF]

open access: yes, 1993
The databases for solid breeder ceramics (Li{sub 2},O, Li{sub 4}SiO{sub 4}, Li{sub 2}ZrO{sub 3} and LiAlO{sub 2}) and beryllium multiplier material are critically reviewed and evaluated. Emphasis is placed on physical, thermal, mechanical, chemical stability/compatibility, tritium, and radiation stability properties which are needed to assess the ...
Billone, M. C.   +5 more
openaire   +2 more sources

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

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