Results 191 to 200 of about 461,778 (244)

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Suicidality, care access, and knowledge deficits lead priorities on blast overpressure/mTBI in an Australian special operations forces survey and their implications for evolving U.S. Warfighter brain health initiatives. [PDF]

Front Public Health
Ivory RA, Scanlan P, Ditzel R, Meabon JS.   +3 more
europepmc   +1 more source

A Dispersant‐Driven Carbon‐Binder Domains Homogeneity in High‐Energy‐Density Electrodes for Lithium‐Ion Batteries

Advanced Science, EarlyView.
A polar dispersant, aromatic‐functionalized polyacrylate (AFPA), enables the formation of a uniform CBD network by enhancing miscibility with PVDF and suppressing phase separation. This leads to α‐phase crystallization of PVDF and aligned CNT networks within the CBD, resulting in well‐connected structures that improve cohesion, electron/ion transport ...
Da‐Sol Kwon, Min Young Seo, Jinho Ahn, Yea‐Ji Jeong, Woohyeon Shin, Wonseok Ko, Min Jeong Kim, Jiny Lee, Won‐Yong Jeon, Min‐Jae Choi, Kwang In Kim, Jin Ju Eom, Sang Yeop Oh, Honghee Lee, Joona Bang, Jongsoon Kim, YongJoo Kim, Jung‐Keun Yoo   +17 more
wiley   +1 more source

Research progress on biomarkers of blast lung injury: Transition from traditional indicators to novel molecular markers. [PDF]

iScience
Wang H, Yang N, Li L, Fan X, Zhang Y, Ma N, Li X, Yu B, Ma J, Lu Q, Gao J.   +10 more
europepmc   +1 more source

Diverging Liquid–Liquid Phase Separation Behavior of Different Recombinant Major Ampullate Spidroins

Advanced Science, EarlyView.
Fibers spun from the MaSp1‐derivative as well as MaSp1‐MaSp2‐mixtures provide a deeper insight into the assembly process of the spidroins and how hierarchical architectures of spider silk fibers could be achieved. ABSTRACT Spider silk fibers show exceptional mechanical properties, based on their underlying spider silk proteins (spidroins) as well as a ...
Tim Schiller, Cheryl Hayashi, Thomas R. Scheibel   +2 more
wiley   +1 more source

Decomposition and separation of vibration waves from blasting demolition of tall buildings and their component characteristics. [PDF]

Nat Commun
Yao Y, Kang Y, Jia Y, Sun J, Xie X.
europepmc   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

REAPER: a project-centric workflow layer for comparative repeatome analysis. [PDF]

Front Plant Sci
Ulyanov DS, Yurkina AI, Voronezhskaya VS, Ulyanova AA, Kroupin PY, Divashuk MG.   +5 more
europepmc   +1 more source

Supercapacitor Safety: Overcharge‐Induced Failure Mechanisms in Electrochemical Double‐Layer Capacitors

Advanced Science, EarlyView.
Time‐resolved synchrotron radiography reveals the internal evolution of electrochemical double‐layer capacitors under abusive overcharge. EDLCs are shown to follow a thermally driven failure pathway involving electrolyte decomposition, gas generation, and structural collapse, distinct from chemically driven thermal runaway effects of Lithium‐ion ...
Thomas Dore, Inez Kesuma, Abdus S. Ali, Jonas Pfaff, Yuxiao Jin, Rosalie Hamill, Mark Buckwell, Hamish Reid, Thomas Finco, Zeyu Sun, Yuanze Li, Sebastian Schopferer, Siegfried Nau, Nils Böttcher, Henning Markötter, Alexander J. E. Rettie, James Robinson, Paul R. Shearing, Alexander Rack, Thomas S. Miller   +19 more
wiley   +1 more source

Military Occupational Blast Exposure: Definition, Operationalization, and Validation of a Reproducible Risk Classification Metric. [PDF]

J Head Trauma Rehabil
Martindale SL, Rowland JA, Belding JN, Amuan ME, Kennedy E, Nguyen H, Brenner LA, Stewart IJ, Cifu DX, Pugh MJ.   +9 more
europepmc   +1 more source