Results 191 to 200 of about 165,152 (266)
Intensive Chemotherapy With or Without Midostaurin in Adults ≥ 60 Years Old With FLT3‐Mutated AML: A FILO‐DATAML‐PETHEMA Real‐World Study
American Journal of Hematology, EarlyView.ABSTRACT
The addition of midostaurin (MIDO) to intensive chemotherapy (IC) improves survival in younger adults with FLT3‐mutated acute myeloid leukemia (AML); however, real‐world data in elderly patients (≥ 60 years) are limited. This large, retrospective, multicenter study from three European registries (PETHEMA, FILO, DATAML) evaluated MIDO+IC (n ...Gaspar Aspas Requena, Pau Montesinos, Emilie Bérard, Sarah Bertoli, Rebeca Rodríguez‐Veiga, Celestine Simand, Laura Torres, Pierre Peterlin, Mar Tormo, Rudy Birsen, Juan Miguel Bergua‐Burgues, Emmanuelle Tavernier, Teresa Bernal del Castillo, Martin Carré, Cristina Gil, Adrien Contejean, Eduardo Rodríguez‐Arbolí, Corentin Orvain, Carlos Rodríguez‐Medina, Lauren Veronese, Maria Jose Sayas Lloris, Eric Delabesse, Josefina Serrano, Ariane Mineur, María García‐Fortes, Romain Guieze, Maria Luz Amigo, Arnaud Pigneux, Lorenzo Algarra Algarra, Christian Recher, Pierre‐Yves Dumas, David Martínez‐Cuadrón +31 morewiley +1 more sourceSelinexor and Venetoclax Combination in Patients With Relapsed or Refractory Acute Myeloid Leukemia
American Journal of Hematology, EarlyView.ABSTRACT
Preclinical studies showed a synergistic antileukemia activity with combination of selective XPO1 inhibitor selinexor (SEL) and venetoclax (VEN), with potential to overcome VEN resistance by reducing the anti‐apoptotic protein MCL1. In an investigator‐sponsored, open‐label, phase Ib study (NCT03955783), adult patients with relapsed or ...Somedeb Ball, Farrukh T. Awan, Ben K. Tomlinson, Tess Stopczynski, Melissa A. Fischer, Zhiguo Zhao, Kateryna Fedorov, Ashwin Kishtagari, Sanjay R. Mohan, Gregory D. Ayers, Michael T. Byrne, Michael R. Savona +11 morewiley +1 more sourceThe Slope of Circulating Blast Clearance Does Not Predict Disease Relapse After Allogeneic Stem Cell Transplantation
, 2011 Aleksandr Lazaryan, Nelli Bejanyan, Lisa Rybicki, Shawnda Tench, S Andresen, Ronald Sobecks, Robert M. Dean, Brad Pohlman, M Kalaycio, Brian J. Bolwell, Edward A. Copelan +10 moreopenalex +1 more sourceCombined Long‐Read Genome and Transcriptome Sequencing Establishes Novel Variants in MEGF8 as the Cause for Carpenter Syndrome Type 2
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT
Carpenter syndrome type 2 (CRPT2) is a rare autosomal recessive disease mainly characterized by craniosynostosis and polysyndactyly. CRPT2 is the rarer subtype of Carpenter syndrome (CRPTS) and is caused by biallelic variants in the multiple epidermal growth factor‐like domains 8 gene (MEGF8).Kiana Rashidi, Bhavi P. Modi, Phillip A. Richmond, Massimo Mangino, Loryn Byres, Cassie McDonald, Joshua Dalmann, Simran Samra, Kate L. Del Bel, Anna Lehman, Jessica L. Zambonin, Stuart E. Turvey +11 morewiley +1 more sourceEFFECT OF DIFFERENT BIDM MODULES ON MANAGEMENT OF RICE BLAST DISEASE AND ITS IMPACT ON YIELD OF BASMATI PADDY
Himendra Raghuvanshi, S Biswas, Y Balgude, A Gaikwad, V Choudhary, K Kumar, Sahu Bhi, I Muthappa, S Das, A, R Dean, J Van Kan, Z Pretorius, K Hammond-Kosack, Pietro Di, P Spanu, J Rudd, M Dickman, R Kahmann, J Ellis, G Heera, J Lore, T Thind, M Hunjan, R Goel, D Mishra, A Sinha, D Pandit, A Singh, V Razdan, S Singh, V Singh, D Kumar, R Persaud, D Saravanakumar, M Persaud, G Seepersad, P Sharma, S Sugha, B Singh, A Lal, Abhilasha, S Sobita, P Skamnioti, S Gurr, S Sunder, R Singh, D Dodan, R Yadav, A Yadav, Y.-Y Zhu, H Fang, Y.-Y Wang, J Fan, S.-S Yang, T Mew, C Mundt +56 moreopenalex +1 more sourcePathogenic Variation and Molecular Characterization of Pyricularia oryzae, Causal Agent of Rice Blast Disease in Tanzania
, 2015 C. Chuwa, R. B. Mabagala, M Muasya Reuben, A Anwar, M Teli, G Bhat, G Parray, Wani, L Babujee, S Gnanamanickham, Z Bhat, M Ahangar, G Sanghera, T Mubarak, J Bonman, T Dios, J Bandong, E Lee, B Bussaban, S Lumyong, P Lumyong, T Seelanan, D Park, E Mckenzie, H Chen, B Chen, D Zhang, Y Xie, Q Zhang, F Correa-Victoria, R Zeigler, B Couch, L Kohn, M Dar, S Hussain, A Darzi, S Bhat, H Dinh, T Noda, P Du, M Filippi, G Silva, V Silva-Lobo, M Crtes, A Moraes, A Prabhu, M Gad, N Ibrahim, T Bora, E Gandalera, C Divina, J Dar, M Ghazanfar, A Habib, S Sahi, M Hosseini-Moghaddam, J Soltani, Y Jiaa, Y Wamisheb, B Zhouc, S Kang, Y Lee, V Karthikeyan, R Rajarajan, S Gnanamanickam, R Khadka, S Shrestha, H Manandhar, G, A Kumar, S Kumar, R Kumar, V Kumar, L Prasad, N Kumar, D Singh, H Leung, E Borromeo, M Bernardo, J Notteghem, Y Li, S Liang, X Yan, H Wang, D Li, D Soanes, N Talbot, Z Wang, W Zhengyi, S Mathur, Kongsdal Olga, M Noguchi, N Yasuda, Y Fujita, S Padmanabhan, N Chakrabarti, S Mathur, J Veeraraghavan, A Prabhu, M Filippi +99 moreopenalex +1 more source