Results 31 to 40 of about 15,213 (294)
Improving the performance of concrete using 3D fibres
, 2012 This paper examines whether 3D fibre reinforcement can improve the toughness and flexural strength of concrete, when compared to equal dosage of straight steel fibres. This work was carried out to determine structural qualities that may lead to potential
Richardson, Alan, Heather, Marcus
core +1 more source
Management of Orthopedic Blast Injuries
, 2020 Over the past two decades, the complexity and severity of orthopedic blast injuries have increased significantly. This has been the case not only with the combat operations undertaken in Iraq and Afghanistan but also with casualties sustained in ...
Jason P. Welter +3 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta +6 more
wiley +1 more source
Di-san junyi daxue xuebao, 2019 Objective To construct a three-dimensional finite element model of human maxillofacial structures to dynamically simulate blast injuries in different maxillofacial regions and analyze the biomechanical characteristics of skull base injuries caused by ...
ZHOU Xuhua +3 more
doaj +1 more source
Indian Journal of Dental Research, 2021 An explosion is caused by conversion of solid, liquid into gas with resultant energy release. Blast injuries of large tyres are similar to injuries resulting from landmine explosions.
R Sathyanarayanan +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The interaction and pharmacological modulation of the cardiorespiratory responses to primary thoracic blast injury, haemorrhage resuscitation [PDF]
, 2002 Blast injuries represent a problem for civilian and military populations. The response to thoracic blast injury involves a reflex bradycardia, hypotension and apnoea.
Sawdon, Mariana Annette +2 more
core
Injury scoring systems for blast injuries: a narrative review
, 2021 Injury scoring systems can be used for triaging, predicting morbidity and mortality, and prognosis in mass casualty incidents. Recent conflicts and civilian incidents have highlighted the unique nature of blast injuries, exposing deficiencies in current ...
Pearce, A Phill +3 more
core +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source