Results 71 to 80 of about 468,539 (282)
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
Advanced Science, EarlyView.Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan +10 more
wiley +1 more source
MODELING THE EFFECTS OF MOSQUE EXPLOSION ON PRAYERS
Yanbu Journal of Engineering and ScienceMosques are temples for Muslims in which five prayers are held a day. The continuous escalation of terrorist threats in general and on mosques, in particular, necessitates the importance of protecting people and infrastructure from the burdens of ...
Ahmed Bagabir
doaj +2 more sources
Advanced Science, EarlyView.Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.
Lin Chen +12 more
wiley +1 more source
Advanced Science, EarlyView.Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo +10 more
wiley +1 more source
Experimental animal models for studies on the mechanisms of blast induced neurotrauma
Frontiers in Neurology, 2012 A blast injury is a complex type of physical trauma resulting from the detonation of explosive compounds and has become an important issue due to the use of improvised explosive devices (IED) in current military conflicts. Blast induced neurotrauma (BINT)
Mårten eRisling, Johan eDavidsson
doaj +1 more source
Explosions and blast injuries : a primer for clinicians [PDF]
As the risk of terrorist attacks increases in the U.S., disaster response personnel must understand the unique pathophysiology of injuries associated with explosions and must be prepared to assess and treat the people injured by ...
core
Introduction Blast injuries result from exposure to explosions and vary in mechanism and severity. A recent increase in illegal explosions in Sweden highlights the need for improved understanding of related injuries.
Tomas Vedin +2 more
core +1 more source
Medical Challenges in Managing Blast Injuries
, 2018 This is not another chapter about blast injuries but rather a brief summary of the main challenges encountered when treating patients with these catastrophic ...
Mauricio Lynn, Lynn, Mauricio
core +1 more source
Advanced Science, EarlyView.MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant +14 more
wiley +1 more source