Results 121 to 130 of about 30,394 (314)

Experimental and numerical study on protective effect of RC blast wall against air shock wave

open access: yesDefence Technology
Prototype experiments were carried out on the explosion-proof performance of the RC blast wall. The mass of TNT detonated in the experiments is 5 kg and 20 kg respectively. The shock wave overpressure was tested in different regions.
Xin-zhe Nian   +4 more
doaj   +1 more source

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

open access: yesAdvanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng   +14 more
wiley   +1 more source

Microscope-controlled glass bead blasting: a new technique

open access: yes, 2011
Peter Kotschy1, Sascha Virnik2, Doris Christ3, Alexander Gaggl21Private Practice, Vienna, Austria; 2Department of Oral and Maxillofacial Surgery, Central Hospital, Klagenfurt, Austria; 3Klagenfurt, AustriaObjective: The aim of periodontal therapy is the ...
Sascha Virnik   +3 more
core  

Cavity Effects and Prediction in the Vibration of Large-Section Rectangular Coal Roadways Induced by Deep-Hole Bench Blasting in Open-Pit Mines

open access: yesSensors
The dynamic response law of the vibration cavity effect in the adjacent large-section rectangular coal roadways induced by deep-hole bench blasting vibrations was deeply revealed, and the prediction accuracy of the PPV in the coal roadway was improved ...
Anjun Jiang   +4 more
doaj   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

Optimization of drilling and blasting pattern in Meiduk copper mine

open access: yes, 2002
In this paper the procedure for the determination of drilling and blasting patterns in general and that for Meiduk copper mine in particular, has first been described.
Amiri, Ravanbakhsh, Oraee, Kazem
core  

Comprehensive, experimental–simulative structure–property relation investigation of heterogeneous interface bonding by interlocks

open access: yesMaterials & Design
Precision manufacturing demands control over interfacial bonding properties, which relies on understanding the structure–property relationships. The authors applied experimental–simulative approach to investigate these relationships, specifically: a. RVE
Jiajin Li   +5 more
doaj   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

Blasting

open access: yes, 1996
"June 4, 1996."; Discusses whether state blasting laws supersede the recently adopted Rocky Hill blasting ordinances .; Harvested from the web on 2/11 ...
Rose, Veronica,
core  

Study on the Evolution Law of Overlying Rock Collapse Induced by Mining Based on BOTDR

open access: yesApplied Sciences
Based on Brillouin optical time-domain reflectometry (BOTDR) technology, this study integrates laboratory tensile tests and similarity simulation experiments to systematically investigate the relationship between overlying strata collapse and fiber ...
Chenrui Huang   +3 more
doaj   +1 more source

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