Results 191 to 200 of about 122,819 (363)

AI-powered simulation-based inference of a genuinely spatial-stochastic model of early mouse embryogenesis [PDF]

open access: yesarXiv
Understanding how multicellular organisms reliably orchestrate cell-fate decisions is a central challenge in developmental biology. This is particularly intriguing in early mammalian development, where early cell-lineage differentiation arises from processes that initially appear cell-autonomous but later materialize reliably at the tissue level.
arxiv  

Simulated gestation: The social and ethical implications of in vivo fertilisation technology

open access: yesBioethics, EarlyView.
Abstract INVOcell is an in vivo fertilisation device marketed as an alternative to in vitro fertilisation treatment. In this paper, we explore the ethical implications that arise when this device is framed as a type or process of ‘gestation’. We anticipate several effects that may be of ethical interest: marketing in vivo fertilisation as being ...
Ji‐Young Lee   +2 more
wiley   +1 more source

EFFECTS OF ASPIRIN AND PHENYLBUTAZONE ON THE RABBIT BLASTOCYST [PDF]

open access: bronze, 1965
James L. Schardein   +3 more
openalex   +1 more source

METTL16 and YTHDC1 Regulate Spermatogonial Differentiation via m6A

open access: yesCell Proliferation, EarlyView.
The deletion of either Mettl16 or Ythdc1 with Stra8‐Cre disrupted the gene expression related to chromosome organisation and segregation, resulting in aberrant differentiation of spermatogonia and male infertility. ABSTRACT Spermatogenesis is a highly unique and intricate process, finely regulated at multiple levels, including post‐transcriptional ...
Xueying Gu   +6 more
wiley   +1 more source

The Effect of the Reduction of Volume of Blastocoel Cavity before Vitrification on Viability and Quality of In Vitro Mouse Blastocyst through Assessment of Fgf4 Gene Expression

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015
Background and Objectives: Although studies have shown that viability rate of transferred blastocysts in comparison to embryos in previous stages is higher, the viability rate of warmed blastocysts was lower than embryos in other stages.
Ronak Sehati   +3 more
doaj  

Challenges and possible clinical applications of human embryonic stem cell research [PDF]

open access: yes, 2012
Human embryonic stem cells (hESC) are harvested from the inner cell mass of the pre-implantation embryo and possess several unique characteristics. First, they are self-renewing, meaning they can grow indefinitely in an appropriate culture environment ...
De Sutter, Petra   +3 more
core   +1 more source

Inhibition of Hatching of Mouse Blastocysts in vitro by Prostaglandin Antagonists [PDF]

open access: bronze, 1978
John D. Biggers   +3 more
openalex   +1 more source

Organoid Models to Study Human Infectious Diseases

open access: yesCell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu   +4 more
wiley   +1 more source

Exposing dairy bulls to high temperature-humidity index during spermatogenesis compromises subsequent embryo development in vitro [PDF]

open access: yes, 2020
Broekhuijse, Marleen L.W.J.   +10 more
core   +2 more sources

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