Results 191 to 200 of about 133,185 (340)

The attitudes of individuals with or at risk of adult‐onset genetic conditions on reproductive genetic testing: A systematic review

open access: yesJournal of Genetic Counseling, Volume 34, Issue 4, August 2025.
Abstract Individuals who carry a genetic variant for a genetic disease can access reproductive genetic testing in order to prevent the transmission of the gene variant to their children. This systematic review aimed to synthesize the findings from both qualitative and quantitative literature to understand these individuals' attitudes toward pre ...
Shanice Allen   +4 more
wiley   +1 more source

Models of Endocrine‐Disrupting Effects: Human Placental Steroidogenesis

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 137, Issue 2, August 2025.
ABSTRACT Endocrine disruption during pregnancy has gained increasing interest as epidemiological studies report associations of exposures and adverse effects on fetal growth, followed by effects on the growing child and ultimately in the adult. When studying endocrine disruption during pregnancy, the placental steroidogenesis is difficult to model, as ...
Line Mathiesen   +4 more
wiley   +1 more source

Obesity Affects IVF Outcomes and Mevalonic Acid Rescues the Side Effects of Statins on Follicle Growth

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
Obesity reduces in vitro fertilization pregnancy success, with significant decreases in the number of retrieved oocytes, mature oocytes, and cleavage embryos. Mevalonic acid rescues potential productive toxicity of the lipid‐lowering drug simvastatin in follicular development.
Fei Mao   +8 more
wiley   +1 more source

Live birth rate following frozen–thawed blastocyst transfer is higher with blastocysts expanded on Day 5 than on Day 6

open access: yesHuman Reproduction, 2018
L. Ferreux   +10 more
semanticscholar   +1 more source

Placental RTN3L‐dependent ER‐Phagy Contributes to Fetal Testicular Dysplasia Upon Environmental Stress

open access: yesAdvanced Science, Volume 12, Issue 25, July 3, 2025.
Gestational environmental stress activates ER‐phagy by increasing placental Rtn3l mRNA N6‐methyladenosine modification, further inhibiting placental estradiol synthesis and contributing to fetal testicular dysplasia. This study demonstrates the early prevention and treatment of adult male infertility from the perspective of fetal‐derived diseases ...
Ye‐Xin Luo   +17 more
wiley   +1 more source

Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst

open access: yesDevelopment, 2005
D. Strumpf   +6 more
semanticscholar   +1 more source

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