Results 1 to 10 of about 330,577 (263)

Knockdown of KDM5B Leads to DNA Damage and Cell Cycle Arrest in Granulosa Cells via MTF1

Current Issues in Molecular Biology, 2023
KDM5B is essential for early embryo development, which is under the control of maternal factors in oocytes. Granulosa cells (GCs) play a critical role during oocyte mature. However, the role of KDM5B in GCs remains to be elucidated. In the current study,
Yingnan Yang, Yu Cai, Jinjing Guo, Keke Dai, Liang Liu, Zili Chen, Feng Wang, Mingtian Deng   +7 more
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The Novel Competing Endogenous Long Noncoding RNA SM2 Regulates Gonadotropin Secretion in the Hu Sheep Anterior Pituitary by Targeting the Oar-miR-16b/TGF-β/SMAD2 Signaling Pathway

Cells, 2022
Pituitary gonadotropins play a pivotal role in reproduction. Long noncoding RNAs (lncRNAs) have been identified as important regulators in the hypothalamic–pituitary–ovarian (HPO) axis associated with reproduction.
Zhen Wan, Hua Yang, Peiyong Chen, Zhibo Wang, Yu Cai, Xiaolei Yao, Feng Wang, Yanli Zhang   +7 more
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Cumulative live birth rates between GnRH-agonist long and GnRH-antagonist protocol in one ART cycle when all embryos transferred: real-word data of 18,853 women from China

Reproductive Biology and Endocrinology, 2021
Background A consensus has been reached on the preferred primary outcome of all infertility treatment trials, which is the cumulative live birth rate (CLBR).
Jingwei Yang, Xiaodong Zhang, Xiaoyan Ding, Yuting Wang, Guoning Huang, Hong Ye   +5 more
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The transverse diameter of right common femoral vein by ultrasound in the supine position for predicting post-spinal hypotension during cesarean delivery

BMC Anesthesiology, 2021
Background Post-spinal anesthesia hypotension during cesarean delivery is caused by decreased systemic vascular resistance due to the blockage of the autonomic nerves, which is further worsened by inferior vena cava (IVC) compression by the gravid uterus.
Shi-Fa Yao, Yan-Hong Zhao, Jing Zheng, Jie-Yan Qian, Chen Zhang, Zifeng Xu, Tao Xu   +6 more
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Engineered domain-inlaid Nme2Cas9 adenine base editors with increased on-target DNA editing and targeting scope

BMC Biology, 2023
Background Nme2ABE8e has been constructed and characterized as a compact, accurate adenine base editor with a less restrictive dinucleotide protospacer-adjacent motif (PAM: N4CC) but low editing efficiency at challenging loci in human cells.
Ding Zhao, Xun Gao, Jiale Zhou, Jinze Li, Yuqiang Qian, Di Wang, Wenchao Niu, Tao Zhang, Mingyang Hu, Haoyang Xiong, Liangxue Lai, Zhanjun Li   +11 more
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The Genetic Mutation of ANO5 in Rabbits Recapitulates Human Cardiomyopathy

Applied Sciences, 2020
The limb girdle muscular dystrophy type 2L (LGMD2L) is caused by mutations of the ANO5 gene in humans which encodes a 913 amino-acid integral membrane protein.
Tingting Sui, Hongwu Yao, Tao Zhang, Jinze Li, Liangxue Lai, Zhanjun Li   +5 more
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A Study on Genes of Bayanbulak Sheep [PDF]

Asian-Australasian Journal of Animal Sciences, 2013
The average twin lambing rate of Bayanbulak sheep is 2% to 3%. However, a flock of sheep with a close genetic relationship and an average of 2 to 3 lambs per birth has been found recently.
Beiyao Zuo, Hongguang Qian, Ziyu Wang, Xu Wang, Noor Nisa, Aierdin Bayier, Shijia Ying, Xiaolong Hu, Changhai Gong, Zhiqin Guo, Feng Wang   +10 more
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ASSESSMENT OF THE EFFICACY O SEPHADEX FILTRATION OF BUFFALO SPERMATOZOA FOR CRYOPRESERVATION [PDF]

Veterinary Medical Journal - Giza, 2006
In the present study, two experiments were conducted. The first experiment aimed to study the influence of buffalo bull semen filtration throughout different grades of sephadex columns (G-25, G-50, G-75, G-100 and G-200) on semen quality.
MAHA ZIADA, MONA ALAA EL-DEEN, A ZAKY, KARIMAN HASSANIN   +3 more
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CRISPR/Cas9-mediated mutation of tyrosinase (Tyr) 3′ UTR induce graying in rabbit

Scientific Reports, 2017
The 3′ untranslated regions (UTRs), located at the end of mRNA molecules, are believed to play a role in RNA replication and/or protein translation. Mutations in the tyrosinase (Tyr) gene are known to cause recessive albinism in humans and other species.
Yuning Song, Yuxin Xu, Jichao Deng, Mao Chen, Yi Lu, Yong Wang, Haobin Yao, Lina Zhou, Zhiquan Liu, Liangxue Lai, Zhanjun Li   +10 more
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Robust generation of transgenic mice by simple hypotonic solution mediated delivery of transgene in testicular germ cells

Molecular Therapy: Methods & Clinical Development, 2016
Our ability to decipher gene sequences has increased enormously with the advent of modern sequencing tools, but the ability to divulge functions of new genes have not increased correspondingly.
Abul Usmani, Nirmalya Ganguli, Subodh K Jain, Nilanjana Ganguli, Rajesh Kumar Sarkar, Mayank Choubey, Mansi Shukla, Hironmoy Sarkar, Subeer S Majumdar   +8 more
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