Results 1 to 10 of about 481,641 (307)
Advances in embryo and reproductive genetics have influenced clinical approaches to overcome infertility. Since the 1990s, many attempts have been made to decipher the genetic causes of infertility and to understand the role of chromosome aneuploidies in embryo potential.
Carmen Rubio, Carlos Simón
openaire +2 more sources
Pituitary gonadotropins play a pivotal role in reproduction. Long noncoding RNAs (lncRNAs) have been identified as important regulators in the hypothalamic–pituitary–ovarian (HPO) axis associated with reproduction.
Zhen Wan +7 more
doaj +1 more source
Knockdown of KDM5B Leads to DNA Damage and Cell Cycle Arrest in Granulosa Cells via MTF1
KDM5B is essential for early embryo development, which is under the control of maternal factors in oocytes. Granulosa cells (GCs) play a critical role during oocyte mature. However, the role of KDM5B in GCs remains to be elucidated. In the current study,
Yingnan Yang +7 more
doaj +1 more source
Background A consensus has been reached on the preferred primary outcome of all infertility treatment trials, which is the cumulative live birth rate (CLBR).
Jingwei Yang +5 more
doaj +1 more source
The Effect of Light on Embryos and Embryo Culture [PDF]
In oviparous animals, the egg hatches outside of the body and is exposed to light; in some cases throughout the development of the fetus. In mammals, fertilization and the growth of embryos in vivo occurs in the dark but in human IVF, these embryos are exposed to variable light sources and intensities.
Kimball O. Pomeroy, Michael Reed
openaire +1 more source
Background Post-spinal anesthesia hypotension during cesarean delivery is caused by decreased systemic vascular resistance due to the blockage of the autonomic nerves, which is further worsened by inferior vena cava (IVC) compression by the gravid uterus.
Shi-Fa Yao +6 more
doaj +1 more source
Background Nme2ABE8e has been constructed and characterized as a compact, accurate adenine base editor with a less restrictive dinucleotide protospacer-adjacent motif (PAM: N4CC) but low editing efficiency at challenging loci in human cells.
Ding Zhao +11 more
doaj +1 more source
The Genetic Mutation of ANO5 in Rabbits Recapitulates Human Cardiomyopathy
The limb girdle muscular dystrophy type 2L (LGMD2L) is caused by mutations of the ANO5 gene in humans which encodes a 913 amino-acid integral membrane protein.
Tingting Sui +5 more
doaj +1 more source
They Can't Have My Embryo: The Ethics of Conditional Embryo Donation [PDF]
There are substantial numbers of frozen embryos in storage that will not be used by those who produced them for their own fertility treatment. One option for such embryos is to donate them to others to use in their fertility treatment.
Eric Blyth +4 more
core +1 more source
Embryo donation parents' attitudes towards donors : comparison with adoption [PDF]
BACKGROUND: Embryo donation produces a family structure where neither rearing parent is genetically related to the child, as in adoption. It is not known how embryo donation parents view the donors compared with how adoptive parents view the birth ...
MacCallum, Fiona
core +1 more source

