Results 11 to 20 of about 316,204 (264)
Genes, 2021 Advances in embryo and reproductive genetics have influenced clinical approaches to overcome infertility. Since the 1990s, many attempts have been made to decipher the genetic causes of infertility and to understand the role of chromosome aneuploidies in embryo potential.
Carmen Rubio, Carlos Simón
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The Effect of Light on Embryos and Embryo Culture [PDF]
Journal of Reproductive and Stem Cell Biotechnology, 2012 In oviparous animals, the egg hatches outside of the body and is exposed to light; in some cases throughout the development of the fetus. In mammals, fertilization and the growth of embryos in vivo occurs in the dark but in human IVF, these embryos are exposed to variable light sources and intensities.
Kimball O. Pomeroy, Michael Reed
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Proceedings of the National Academy of Sciences, 2011 Generation of transgenic mice by pronuclear DNA injection into fertilized eggs has been well-established for over 30 y (1). However, it remains a rather crude approach: injected sequences randomly insert as concatamers, they can be mutagenic, and they have variable expression depending on the site of integration, a phenomenon called position effects ...
Janet, Rossant +2 more
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Bioscientifica Proceedings, 2020 Nuclear transfer for the study of differentiation in amphibians has been used since the 1950s, but not until recently have the same procedures been applied successfully to some mammals. Nuclear transfer, as developed for the amphibian, is successful in sheep, cattle, rabbit, and pig, but not mouse embryos.
R S, Prather, N L, First
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CRISPR/Cas9-mediated mutation of tyrosinase (Tyr) 3′ UTR induce graying in rabbit
Scientific Reports, 2017 The 3′ untranslated regions (UTRs), located at the end of mRNA molecules, are believed to play a role in RNA replication and/or protein translation. Mutations in the tyrosinase (Tyr) gene are known to cause recessive albinism in humans and other species.
Yuning Song +10 more
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Molecular Therapy: Methods & Clinical Development, 2016 Our ability to decipher gene sequences has increased enormously with the advent of modern sequencing tools, but the ability to divulge functions of new genes have not increased correspondingly.
Abul Usmani +8 more
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Scientific Reports, 2022 Somatic cell nuclear transfer technique (SCNT) has proved to be an outstanding method of multiplication of elite animals but accompanied with low efficiency and live birth rate of cloned animals. Epigenetic alterations of DNA has been one of the culprits
Shivani Malpotra +4 more
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Scientific Reports, 2017 Spermatogenesis can be affected by nutrition, which operates through normal physiological processes by changing the testicular mass and hormone levels profoundly.
Yanli Zhang +9 more
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[Chimeric embryos and pseudo-embryos: An alternative to human embryos for research].
Medecine sciences : M/S, 2021 L’étude du développement humain est indispensable afin d’approfondir nos connaissances et, à long terme, perfectionner nos stratégies thérapeutiques dans les domaines de la médecine de la reproduction et de la médecine régénératrice. Face à la limite d’accès aux embryons surnuméraires et à l’interdiction d’en créer de nouveaux seulement à des fins de ...
Savatier, Pierre +5 more
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IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche
Nature Communications, 2020 The signals regulating the establishment and maintenance of the pluripotent epiblast in human embryos are unclear. Here, the authors use a bioinformatics approach to identify the role of IGF1 in human embryo development, and from this, propose a culture ...
Sissy E. Wamaitha +16 more
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