Down's syndrome (DS) is one of the most commonly known disorders with multiple congenital disabilities. Besides severe cognitive impairment and intellectual disability, individuals with DS also exhibit additional phenotypes of variable penetrance and ...
Yunjie Wang +18 more
doaj +1 more source
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song +15 more
wiley +1 more source
AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep
Anti-Müllerian Hormone (AMH), secreted by granulosa cells (GCs) of preantral follicles, regulates early-stage follicle growth by inhibiting the activation of primordial follicles.
Hui Xu +7 more
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Detrimental effects of lipopolysaccharides on maturation of bovine oocytes [PDF]
Objective Gram-negative bacteria lipopolysaccharide (LPS) has been reported to be associated with uterine impairment, embryonic resorption, ovarian dysfunction, and follicle retardation.
Shanjiang Zhao +5 more
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Pre-implantation maternal uterine effects on embryo growth and development : an investigation using models of maternal constraint in sheep : a thesis presented in fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science, Massey University, Turitea, Palmerston North, New Zealand [PDF]
Listed in 2017 Dean's List of Exceptional ThesesPrenatal development and growth are critical to survival of the fetus and neonate. Recent evidence suggests that a critical period for determining growth is the pre-implantation period of pregnancy during
Fermin, Lisanne Monique
core
The growth of plant embryos in vitro. Preliminary experiments on the role of accessory substances [PDF]
The aseptic culture of plant embryos isolated from the seed dates back to the work of Brown and Morris,(1) Hannig(2) and Dietrich.(3) More recent contributions to our knowledge concerning the culture in vitro of excised embryos have been made by Tukey,(4)
Axtman, Grice, Bonner, James
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
THE IDENTIFICATION OF CHROMOSOMAL POLYMORPHISM IN ONE BREED OF IRAQI SHEEP
A chromosomal analysis of three breeds of Iraqi sheep (Karadi Arabi and Awassi) has been performed on peripheral lymphocytes. The modal chromosome number of all the three breeds was found to be (2n=54XX/54XY) for femal and male respectively.
A. A. Yasseen +3 more
doaj +1 more source
Prospects for transgenesis in the chick [PDF]
Research to develop a useful method for genetic modification of the chick has been on-going since the first demonstrations in the mouse in the 1980s that genetic modification is an invaluable tool for the study of gene function. Manipulation of the chick
Bosselman +52 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

