Results 221 to 230 of about 122,819 (363)

Successful Culture in vitro of Bovine Embryos to the Blastocyst Stage [PDF]

open access: bronze, 1976
Raymond W. Wright   +3 more
openalex   +1 more source

β3‐Adrenoceptor Agonism to Mimic the Biological Effects of Intrauterine Hypoxia: Taking Great Strides Toward a Pharmacological Artificial Placenta

open access: yesMedicinal Research Reviews, Volume 45, Issue 3, Page 842-866, May 2025.
ABSTRACT At different stages of life, from embryonic to postnatal, varying oxygen concentrations modulate cellular gene expression by enhancing or repressing hypoxia‐inducible transcription factors. During embryonic/fetal life, these genes encode proteins involved in adapting to a low‐oxygen environment, including the induction of specific enzymes ...
Luca Filippi   +9 more
wiley   +1 more source

Requirement for STAT3 and its target, TFCP2L1, in self-renewal of naïve pluripotent stem cells in vivo and in vitro

open access: yesBiology Open, 2023
Sophie Kraunsoe   +6 more
doaj   +1 more source

3D Bioprinted Coaxial Testis Model Using Human Induced Pluripotent Stem Cells:A Step Toward Bicompartmental Cytoarchitecture and Functionalization

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
The ability of human induced pluripotent stem cells (hiPSCs) to model developmental processes makes them a promising source for engineering testicular tissues to study in vitro maturation and sperm production. This work describes the first hiPSC‐derived testicular model and shows that it captures functional aspects of prepubertal testicular tissues ...
Meghan A Robinson   +15 more
wiley   +1 more source

The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ

open access: yesAdvanced Science, Volume 12, Issue 15, April 17, 2025.
The placenta expresses much higher levels of PPARγ than fetal adipose tissue. Trophoblastic exosomes transport PPARγ into fetal preadipocytes via fetoplacental circulation and thus regulate adipogenic genes distinct from endogenous PPARγ. Compromised placental PPARγ leads to fetal adipogenesis deficiency and intrauterine growth restriction, reversible ...
Xiaofang Luo   +17 more
wiley   +1 more source

HBimmCue: A Versatile Fluorescent Probe for Multi‐Scale Imaging of Lipid Polarity and Membrane Order in Inner Mitochondrial Membrane

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
HBimmCue is introduced as a fluorescent probe that detects lipid polarity changes in the inner mitochondrial membrane (IMM), reflecting cellular respiration levels. Using fluorescence lifetime imaging (FLIM), IMM lipid heterogeneity is uncovered across various scales, from nanoscale structures in mitochondria to cellular and developmental models ...
Shu Gao   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy