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The mammalian blastocyst

WIREs Developmental Biology, 2016
The blastocyst is a mammalian invention that carries the embryo from cleavage to gastrulation. For such a simple structure, it exhibits remarkable diversity in its mode of formation, morphology, longevity, and intimacy with the uterine endometrium. This review explores this diversity in the light of the evolution of viviparity, comparing the three main
Janet Rossant   +3 more
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Blastocyst metabolism

Reproduction, Fertility and Development, 2015
The mammalian blastocyst exhibits an idiosyncratic metabolism, reflecting its unique physiology and its ability to undergo implantation. Glucose is the primary nutrient of the blastocyst, and is metabolised both oxidatively and through aerobic glycolysis.
David K, Gardner, Alexandra J, Harvey
openaire   +3 more sources

Mechanics of blastocyst morphogenesis

Biology of the Cell, 2017
During pre‐implantation development, the mammalian zygote transforms into the blastocyst, the structure that will implant the embryo in the maternal uterus. Consisting of a squamous epithelium enveloping a fluid‐filled cavity and the inner cell mass, the blastocyst is sculpted by a succession of morphogenetic events.
J. Maître
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To blastocyst or not to blastocyst? That is the question

Human Reproduction, 2001
Recent advances in culture media preparations have allowed for cleavage embryos to be developed to the blastocyst stage. Blastocysts are regarded as having increased implantation potential, and two blastocysts are typically transferred, which reduces the occurrence of high order multiple gestations.
Peter Brinsden   +3 more
openaire   +3 more sources

Estimation of age-dependent decrease in blastocyst euploidy by next generation sequencing: development of a novel prediction model.

Panminerva Medica (Testo stampato), 2019
BACKGROUND We developed a model to estimate the female age-dependent decrease in blastocyst euploidy and the impact of blastocyst cohort size on the likelihood of having at least one euploid blastocyst for transfer.
S. Esteves   +6 more
semanticscholar   +1 more source

Antigenicity of the mouse blastocyst

Canadian Journal of Zoology, 1972
It has been shown that development of mouse blastocysts, transplanted to ectopic sites in mice, can be inhibited by preimmunizing the host against transplantation antigens of the donor strain. Similar inhibition can be produced by repeated transplants of blastocysts to extrauterine sites in one host.
D A James, S M Yoshida
openaire   +3 more sources

Associations of blastocyst features, trophectoderm biopsy and other laboratory practice with post-warming behavior and implantation

Human Reproduction, 2018
STUDY QUESTION Are trophectoderm biopsy or other pre-vitrification features or laboratory practices associated with differences in blastocyst post-warming behavior (degeneration, re-expansion and live birth after single embryo transfer (SET))?
D. Cimadomo   +13 more
semanticscholar   +1 more source

Blastocyst freezing

European Journal of Obstetrics & Gynecology and Reproductive Biology, 2004
Blastocyst are preimplantation embryos that have successfully passed the critical step of genomic activation and have so a high developmental potential, thus allowing to reduce the number of embryos transferred. Blastocyst culture and freezing have really started in IVF programs in the early nineties, when it was possible to obtain good blastocysts ...
openaire   +2 more sources

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