Results 11 to 20 of about 7,102 (163)

CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen Blastomyces dermatitidis

open access: yesmBio, 2018
Blastomyces dermatitidis is a human fungal pathogen of the lung that can lead to disseminated disease in healthy and immunocompromised individuals. Genetic analysis of this fungus is hampered by the relative inefficiency of traditional recombination ...
Gregory C. Kujoth   +7 more
doaj   +3 more sources

Blastomyces: Why Be Dimorphic? [PDF]

open access: yesJournal of Patient-Centered Research and Reviews, 2016
In introducing the infectious disease focus for this edition of the Journal of Patient-Centered Research and Reviews, the author describes the unsolved mysteries surrounding the dimorphic fungus Blastomyces and the related pathogenesis of pulmonary ...
Dennis J. Baumgardner
doaj   +2 more sources

Blastomyces gilchristii as Cause of Fatal Acute Respiratory Distress Syndrome

open access: yesEmerging Infectious Diseases, 2016
Since the 2013 description of Blastomyces gilchristii, research describing the virulence or clinical outcome of B. gilchristii infection has been lacking. We report molecular evidence of B.
Daniel Dalcin   +4 more
doaj   +2 more sources

Autochthonous Blastomyces dermatitidis, India

open access: yesEmerging Infectious Diseases
Blastomyces spp. fungi, the causal agent of blastomycosis, are common in North America but do occur in other areas of the world. The most prevalent pathogen in the genus is B. dermatitidis. Most B. dermatitidis isolates originate from North America, but
Anuradha Chowdhary   +6 more
doaj   +2 more sources

Red Fox as Sentinel for Blastomyces dermatitidis, Ontario, Canada

open access: yesEmerging Infectious Diseases, 2016
Blastomyces dermatitidis, a fungus that can cause fatal infection in humans and other mammals, is not readily recoverable from soil, its environmental reservoir. Because of the red fox’s widespread distribution, susceptibility to B.
Nicole M. Nemeth   +5 more
doaj   +2 more sources

Disseminated blastomycosis presenting with genitourinary abscesses

open access: yesUrology Case Reports, 2023
A 25 year old male presented with several weeks of fevers and testicular pain. Workup demonstrated scrotal and prostatic abscesses. Fluid from these following surgical drainage revealed Blastomyces dermatitidis. He was treated with 12 months of oral anti-
Tyler A. Wittmann   +2 more
doaj   +1 more source

Pharmacokinetics of isavuconazole in healthy cats after oral and intravenous administration

open access: yesJournal of Veterinary Internal Medicine, 2022
Background Isavuconazole is a triazole antifungal drug that has shown good efficacy in human patients. Absorption and pharmacokinetics have not been evaluated in cats.
Dennis J. Woerde   +2 more
doaj   +1 more source

Blastomycosis: A Review of Mycological and Clinical Aspects

open access: yesJournal of Fungi, 2023
Blastomycosis is caused by a thermally dimorphic fungus that thrives in moist acidic soil. Blastomyces dermatitidis is the species responsible for most infections in North America and is especially common in areas around the Great Lakes, the St. Lawrence
Kathleen A. Linder   +2 more
doaj   +1 more source

Direct Tissue PCR and Genotyping for Species Identification in a Case of Laryngeal Blastomycosis

open access: yesEar, Nose & Throat Journal, 2023
Otolaryngologic manifestations of infection with Blastomyces species are extremely rare and restricted geographically to recognized endemic regions. Here, we describe a case of laryngeal blastomycosis that presented as slowly progressive dysphonia. While
Thomas R. Fritsche MD, PhD   +5 more
doaj   +1 more source

Disseminated Blastomycosis Presenting as Oligoarthritis, Pneumonia, and Skin Disease in an Immunocompetent Child

open access: yesCase Reports in Pediatrics, 2021
Blastomyces species (spp) can cause clinical disease affecting nearly every organ system, including the skeletal system. However, isolated joint involvement without concurrent osteomyelitis is rare, especially in children.
Emily Schildt, Robyn Bockrath
doaj   +1 more source

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