RNA Sequencing-Based Genome Reannotation of the Dermatophyte Arthroderma benhamiae and Characterization of Its Secretome and Whole Gene Expression Profile during Infection. [PDF]
Dermatophytes are the most common agents of superficial mycoses in humans and animals. The aim of the present investigation was to systematically identify the extracellular, possibly secreted, proteins that are putative virulence factors and antigenic ...
Barbara Methe +11 more
core +11 more sources
The Schizosaccharomyces pombe Map4 adhesin is a glycoprotein that can be extracted from the cell wall with alkali but not with β-glucanases and requires the C-terminal DIPSY domain for function [PDF]
El pdf del artículo es la versión pre-print.In fungi, cell adhesion is required for flocculation, mating and virulence, and it is mediated by covalently bound cell wall proteins termed adhesins. Map4, an adhesin required for mating in Schizosaccharomyces
Reza Sharifmoghadam, Mohammad +1 more
core +2 more sources
Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li +13 more
wiley +1 more source
Experimental infections with Paracoccidioides brasiliensis obtained from armadillos: comparison to clinical isolates [PDF]
Paracoccidioides brasiliensis causes paracoccidioidomycosis (PCM) that is one of the most prevalent systemic human mycoses in Latin America. Armadillos show a high incidence of PCM infection and could, therefore, be a natural reservoir for this fungus ...
BAGAGLI, Eduardo +4 more
core +1 more source
Abstract The diagnosis of autoimmune hepatitis (AIH) is supported by the presence of elevated transaminases, hypergammaglobulinemia, liver biopsy consistent with AIH, and the presence of AIH autoantibodies. In this case presentation, we highlight the challenges associated with diagnosing AIH in a patient with inflammatory bowel disease (IBD) who ...
Benjamin J. Malamet +5 more
wiley +1 more source
Blastomycosis in Northwestern Ontario, 2004 to 2014
Blastomycosis is an invasive fungal disease caused by Blastomyces dermatitidis and the recently discovered Blastomyces gilchristii. The medical charts of 64 patients with confirmed cases of blastomycosis in northwestern Ontario during a 10-year period ...
Daniel Dalcin, Syed Zaki Ahmed
doaj +1 more source
Human and Canine Pulmonary Blastomycosis, North Carolina, 2001–2002
We investigated a cluster of blastomycosis in 8 humans and 4 dogs in a rural North Carolina community. Delayed diagnosis, difficulty isolating Blastomyces dermatitidis in nature, and lack of a sensitive and specific test to assess exposure make outbreaks
Pia D.M. MacDonald +4 more
doaj +1 more source
Invasive fungal infections (IFIs) are a leading cause of morbidity and mortality in children with hematological malignancies as well as those undergoing hematopoietic stem cell transplantation (HSCT). Extreme immunological dysregulation secondary to severe neutropenia, T‐cell lymphopenia, graft‐versus‐host disease (GVHD), intensive chemotherapy ...
Matin Pourghasem +11 more
wiley +1 more source
Blastomycosis Presenting as Multiple Splenic Masses
Blastomyces dermatitidis is a fungus that causes a wide spectrum of disease in humans. The clinical and pathological entity of splenic abscess due to blastomycosis is extremely rare.
Tahir Ijaz +5 more
doaj +1 more source
Blastomyces gilchristii as Cause of Fatal Acute Respiratory Distress Syndrome
Since the 2013 description of Blastomyces gilchristii, research describing the virulence or clinical outcome of B. gilchristii infection has been lacking. We report molecular evidence of B.
Daniel Dalcin +4 more
doaj +1 more source

