Phylogeographic Analysis of Blastomyces dermatitidis and Blastomyces gilchristii Reveals an Association with North American Freshwater Drainage Basins [PDF]
Blastomyces dermatitidis and Blastomyces gilchristii are dimorphic fungal pathogens that cause serious pulmonary and systemic infections in humans. Although their natural habitat is in the environment, little is known about their specific ecologic niche ...
Elizabeth M Brown
exaly +6 more sources
Red Fox as Sentinel for Blastomyces dermatitidis, Ontario, Canada [PDF]
Blastomyces dermatitidis, a fungus that can cause fatal infection in humans and other mammals, is not readily recoverable from soil, its environmental reservoir. Because of the red fox’s widespread distribution, susceptibility to B.
Nicole M. Nemeth +5 more
doaj +5 more sources
A rare case of Blastomyces dermatitidis brain abscess in an immunocompetent host [PDF]
Here we present a case of a 41-year old immunocompetent female from central Maryland, who presented with new onset seizures. Magnetic resonance imaging of brain revealed a solitary ring-enhancing lesion.
Magdalena Slomka, James Doub
doaj +4 more sources
Blastomyces dermatitidis Septic Arthritis in a Renal Transplant Patient. [PDF]
Blastomycosis is a rare endemic fungal infection caused by the dimorphic fungus Blastomyces dermatitidis. It is more likely to occur in persons living in areas of the United States and Canada, which border the Ohio and Mississippi River Valleys and the ...
Ploom S +3 more
europepmc +3 more sources
Phylogenetic Analysis Reveals a Cryptic Species Blastomyces gilchristii, sp. nov. within the Human Pathogenic Fungus Blastomyces dermatitidis [PDF]
Analysis of the population genetic structure of microbial species is of fundamental importance to many scientific disciplines because it can identify cryptic species, reveal reproductive mode, and elucidate processes that contribute to pathogen evolution.
Elizabeth M Brown, Sean X Zhang
exaly +5 more sources
Autochthonous Blastomyces dermatitidis, India [PDF]
Blastomyces spp. fungi, the causal agent of blastomycosis, are common in North America but do occur in other areas of the world. The most prevalent pathogen in the genus is B. dermatitidis. Most B. dermatitidis isolates originate from North America, but
Anuradha Chowdhary +6 more
doaj +3 more sources
The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia [PDF]
Three closely related thermally dimorphic pathogens are causal agents of major fungal diseases affecting humans in the Americas: blastomycosis, histoplasmosis and paracoccidioidomycosis.
José F Muñoz +2 more
exaly +5 more sources
Ribosomal RNA gene sequencing for early diagnosis of Blastomyces dermatitidis infection [PDF]
Prompt detection and identification of fungal pathogens at the genus and species level is critical in order to provide timely antifungal therapy. Here, we highlight the vital role of molecular diagnostics in achieving a fast and definitive diagnosis of ...
Sejal Morjaria +8 more
doaj +3 more sources
Changing Patterns of Disease Severity in Blastomyces dermatitidis Infection, Quebec, Canada [PDF]
This retrospective multicenter cohort study assessed temporal changes in the severity and mortality rate of blastomycosis in Quebec, Canada, and identified risk factors for death in patients with blastomycosis in 1988–2016. The primary outcome was 90-day
Alex Carignan +8 more
doaj +3 more sources
CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen
Blastomyces dermatitidis is a human fungal pathogen of the lung that can lead to disseminated disease in healthy and immunocompromised individuals. Genetic analysis of this fungus is hampered by the relative inefficiency of traditional recombination ...
Gregory C. Kujoth +7 more
doaj +3 more sources

