Results 101 to 110 of about 13,955 (223)
ABSTRACT Background The success of minimally invasive bleb surgery (MIBS) such as the PreserFlo MicroShunt (PFMS) is limited by post‐operative bleb fibrosis. Current clinical practice prescribes the use of off‐label cytotoxic antimetabolites such as Mitomycin C (MMC) as antifibrotic therapy.
Zoe Pasvanis+3 more
wiley +1 more source
Noriko Kato,1,2 Genichiro Takahashi,1,2 Koichi Kumegawa,1,2 Yoshiaki Kabata,1,2 Hiroshi Tsuneoka1 1Department of Ophthalmology, Jikei University, School of Medicine, 2Katsushika Medical Center, Tokyo, Japan Background: We investigated indications and ...
Kato N+4 more
doaj
Our mouse model with a c.259G>A transition in PRPS1 showed a significant decrease in the number of hair cells and SGN counts at 48 weeks of age and a reduction in Prps1 enzymatic activity in the KI mouse. This model will serve as a valuable tool for developing therapeutic strategies.
Denise Yan+6 more
wiley +1 more source
Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen+9 more
wiley +1 more source
Managing a patient with open-angle glaucoma: a case study. [PDF]
How would a panel of experts manage the case presentation of Mr AA
Abdull, Mohammed M, Kyari, Fatima
core +2 more sources
Endometrial adenosarcoma in the setting of a germline DICER1 mutation: A case report [PDF]
Babb, Sheri+4 more
core +3 more sources
Abstract Background Temporohyoid osteoarthropathy (THO) is characterised by bone proliferation and cartilage ossification caused by infectious and degenerative conditions, amongst others. Objectives To describe the variable appearance of the temporohyoid joint (THJ) on computed tomography (CT) and investigate associations between CT changes and ...
Rupert F. Dash+3 more
wiley +1 more source
Semicircular canal morphology in Rodentia and its relationship to locomotion
Here, we present a selection of rodent inner ear 3D models in the lateral view, with rodents from seven locomotor categories (left to right: fossorial, semifossorial, semiaquatic, terrestrial, ricochetal, arboreal, and gliding). Semicircular canal (SCC) morphology, including radius of curvature and shape, can be differentiated between specialized forms
Lily Hou+4 more
wiley +1 more source
The Current State of Clinical Diagnostic Algorithms for Mucosal Oral Lesions: A Scoping Review
ABSTRACT Background Diagnosing oral lesions remains challenging for many dentists. Despite the availability of diagnostic algorithms, there is a dearth of comprehensive evidence synthesis and a discussion on their clinical and pedagogical applicability.
Mohammed Al‐Shehri+7 more
wiley +1 more source