Results 161 to 170 of about 1,947,962 (285)

Real-time Deformation-aware Control for Autonomous Robotic Subretinal Injection under iOCT Guidance [PDF]

arXiv
Robotic platforms provide consistent and precise tool positioning that significantly enhances retinal microsurgery. Integrating such systems with intraoperative optical coherence tomography (iOCT) enables image-guided robotic interventions, allowing autonomous performance of advanced treatments, such as injecting therapeutic agents into the subretinal ...
arxiv  

Cutaneous Side Effects of PD‐1 Inhibitors: A Single‐Center Retrospective Study

International Journal of Dermatology, EarlyView.
ABSTRACT Background The introduction of immune checkpoint inhibitors (ICIs) opened a new era in cancer immunotherapy. In particular, PD‐1 inhibitors have shown remarkable efficacy in various cancers, most notably melanoma. However, the widespread use of immune checkpoint inhibitors comes with the challenge of immune‐related adverse events (irAEs), with
Melánia Pozsgai, Udoh Frieda‐Rex Sebastian, Péter Oláh, Viktória Németh, Rolland Gyulai, Zsuzsanna Lengyel   +5 more
wiley   +1 more source

Delivery management of pregnant blue rubber bleb nevus syndrome patients: a case report and literature review [PDF]

Blue rubber bleb nevus syndrome (BRBNS) is a rare systemic vascular disorder characterized by multifocal venous malformations (VMs). Little is known about the perinatal management of pregnant women with BRBNS owing to the limited number of reported cases.
Chigusa, Yoshitsugu, Egi, Moritoki, Komatsu, Maya, Mandai, Masaki, Mizota, Toshiyuki, Mogami, Haruta, Nagahama, Mie, Nomura, Takashi, Shiraki, Atsuko, Takei, Yui, Yamaguchi, Ayaka   +10 more
core  

Illuminating cell signaling with genetically encoded FRET biosensors in adult mouse cardiomyocytes. [PDF]

, 2018
FRET-based biosensor experiments in adult cardiomyocytes are a powerful way of dissecting the spatiotemporal dynamics of the complicated signaling networks that regulate cardiac health and disease. However, although much information has been gleaned from
Chen-Izu, Ye, Jaradeh, Mark, Jian, Zhong, Reddy, Gopireddy Raghavender, Shi, Qian, Wang, Ying, West, Toni M, Xiang, Yang K   +7 more
core  

Progerin forms an abnormal meshwork and has a dominant-negative effect on the nuclear lamina [PDF]

Progerin, the protein that causes Hutchinson-Gilford progeria syndrome, triggers nuclear membrane (NM) ruptures and blebs, but the mechanisms are unclear.
Fong, Loren G, Jeong, JY Brian, Jung, Hyesoo, Kim, Joonyoung R, Kim, Paul H, Presnell, Ashley, Tran, Anh P, Tu, Yiping, Young, Stephen G   +8 more
core   +1 more source

Semicircular canal morphology in Rodentia and its relationship to locomotion

Journal of Anatomy, EarlyView.
Here, we present a selection of rodent inner ear 3D models in the lateral view, with rodents from seven locomotor categories (left to right: fossorial, semifossorial, semiaquatic, terrestrial, ricochetal, arboreal, and gliding). Semicircular canal (SCC) morphology, including radius of curvature and shape, can be differentiated between specialized forms
Lily Hou, Ornella C. Bertrand, Hiruni N. Mudannayake, Campbell Rolian, Susanne Cote   +4 more
wiley   +1 more source

Analyse UBM du site de filtration après sclérectomie profonde postérieure modifiée utillisant un tube Ex-PRESS? X-50 [PDF]

, 2011
Purpose: To study the filtering site using ultrasound biomicroscopy. (UBM) after posterior deep sclerectomy with Ex-PRESS? X-50 implant in patients undergoing filtering surgery.¦Methods: Twenty-six patients that participated in this prospective, non ...
Chappaz, A.
core  

Interplay between cortical adhesion and membrane bending regulates microparticle formation [PDF]

arXiv
The formation of microparticles requires the bending of the plasma membrane away from the cytosol. The capcity of the cell membrane to form a microparticle, and the rate of membrane deformation, are controlled by multiple factors, including loss of lipid asymmetry (primarily the exposure of phosphatidylserine on the outer leaflet), detachment of the ...
arxiv  

Implications for soluble iron accumulation, oxidative stress, and glial glutamate release in motor neuron death associated with sporadic amyotrophic lateral sclerosis

Neuropathology, EarlyView.
Oxidative stress in sporadic amyotrophic lateral sclerosis (ALS) has been evidenced by accumulation of oxidatively modified products of nucleic acids, lipids, sugars, and proteins in the motor neuron system of brains and spinal cords obtained at autopsy from the patients.
Noriyuki Shibata, Ikuko Kataoka, Yukinori Okamura, Kumiko Murakami, Yoichiro Kato, Tomoko Yamamoto, Kenta Masui   +6 more
wiley   +1 more source

The use of next-generation sequencing in personalized medicine [PDF]

arXiv
The revolutionary progress in development of next-generation sequencing (NGS) technologies has made it possible to deliver accurate genomic information in a timely manner. Over the past several years, NGS has transformed biomedical and clinical research and found its application in the field of personalized medicine.
arxiv