Results 171 to 180 of about 1,947,962 (285)

Phenotypic Spectrum of GNA11 R183C Mosaicism

Pediatric Dermatology, EarlyView.
ABSTRACT Background Many vascular anomalies harbor postzygotic somatic variants in GNAQ and GNA11; however, the phenotype of specific G‐protein variants has not been well described. We report the clinical characteristics of 17 patients with a GNA11 R183C variant.
Donglin Zhang, Luis Fernando Sánchez‐Espino, Marta Ivars, Elena Pope, Amy J. Nopper, Lisa M. Arkin, Megha M. Tollefson, Cinzia E. Lavarino, Maya Muldowney, Nagore Gené Olaciregui, Sonia Paco, Beth A. Drolet, Eulàlia Baselga   +12 more
wiley   +1 more source

AI-driven Alternative Medicine: A Novel Approach to Drug Discovery and Repurposing [PDF]

arXiv
AIAltMed is a cutting-edge platform designed for drug discovery and repurposing. It utilizes Tanimoto similarity to identify structurally similar non-medicinal compounds to known medicinal ones. This preprint introduces AIAltMed, discusses the concept of `AI-driven alternative medicine,' evaluates Tanimoto similarity's advantages and limitations, and ...
arxiv  

Mosaic KRAS Mutation in Schimmelpenning–Feuerstein–Mims Syndrome With Overlapping Oculoectodermal Syndrome and Encephalocraniocutaneous Lipomatosis Features

Pediatric Dermatology, EarlyView.
ABSTRACT We report a patient with clinically confirmed Schimmelpenning–Feuerstein–Mims (SFM) syndrome but many overlapping features with oculoectodermal syndrome (OES) and encephalocraniocutaneous lipomatosis (ECCL). Whole exome sequencing revealed a mosaic KRAS c.436G>A, p.(Ala146Thr) mutation, previously identified in three OES and ECCL patients ...
Hyvönen Hanna, Kettunen Kaisa, Avela Kristiina, Kivirikko Sirpa, Jeskanen Leila, Suominen Sinikka, Salminen Päivi, Hannula‐Jouppi Katariina   +7 more
wiley   +1 more source

Congenital Erosive and Scarring Eruption (CEASE): A Report of Two Cases and Review of the Literature on Congenital Erosive and Vesicular Dermatosis

Pediatric Dermatology, EarlyView.
ABSTRACT Congenital erosive and vesicular dermatosis (CEVD) is a rare condition that typically presents at birth with erosions and vesicles that heal with distinctive reticulate and supple scarring. We report two cases of CEVD in term infants, both of which exhibited unique features.
Lindy Moxham, Sarah Felton, Joseph M. Lam   +2 more
wiley   +1 more source

Critical response to ab interno versus ab externo surgical approach on outflow resistance of a subconjunctival drainage device [PDF]

, 2020
Fellman, Ronald L., Grover, Davinder S., Sheybani, Arsham   +2 more
core   +1 more source

Characterization of mucous membrane pemphigoid in childhood: A multicentre study of 12 cases

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Laure Chêne, Christelle Le Roux‐Villet, Ludovic Martin, Audrey Lasek‐Duriez, Juliette Miquel, Hélène Aubert, Nicolas Macagno, Lucie Vitek, Florian Lombart, Jean‐Jacques Morand, Emmanuelle Bourrat, Christine Chiaverini, Marie‐Aleth Richard, Stéphanie Mallet, Groupe de Recherche de la Société Française de Dermatologie Pédiatrique, Groupe Bulles de la Société Française de Dermatologie   +15 more
wiley   +1 more source

Mapping Bullous Emphysema With Lung Ultrasound: A Prospective Multicentre Study

Respirology, EarlyView.
ABSTRACT Background and Objectives Lung ultrasound holds high diagnostic performance for pleural diseases, notably pneumothorax. Bullous emphysema is a potential differential diagnosis of pneumothorax on ultrasound, but its precise semiology is poorly known.
Kinan El Husseini, Thomas Flament, Sophie Laroumagne, Damien Basille, Mathilde Le Brun, Elise Noël‐Savina, Philippe Richard, Gilles Mangiapan, Elise Artaud‐Macari   +8 more
wiley   +1 more source

Phentolamine Infusion for the Treatment of Norepinephrine Extravasation in a Dog

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To describe a case of clinically significant norepinephrine extravasation in a dog with a successful outcome following the use of subcutaneous phentolamine infusion. Case Summary An 8‐year‐old male neutered Labrador Retriever experienced norepinephrine extravasation from a cephalic, peripheral intravenous catheter while under ...
Grace E. Flynn, Cody I. Riffe, Kathleen M. Aicher, Lance R. Wheeler   +3 more
wiley   +1 more source

Novel treatment of infectious keratitis in canine corneas using ultraviolet C (UV‐C) light

Veterinary Ophthalmology, EarlyView.
Abstract Objective To investigate the therapeutic effect of 275 nm wavelength ultraviolet C (UV‐C) light for treatment of bacterial keratitis in canine corneas using an affordable, broadly available modified handheld device. Methods UV‐C therapy (UVCT) was evaluated in two experiments: in vitro using triplicates of three bacterial genera ...
Bactelius Turicea, Dipak K. Sahoo, Rachel A. Allbaugh, Chloe C. Stinman, Melissa A. Kubai   +4 more
wiley   +1 more source

Effects of intracameral tissue plasminogen activator injection on posterior capsular opacification, fibrin formation, and intraocular pressure in dogs after phacoemulsification

Veterinary Ophthalmology, EarlyView.
Abstract Objective To evaluate whether intracameral tissue plasminogen activator (tPA) injection is effective in regulating posterior capsular opacification (PCO), fibrin formation and intraocular pressure (IOP) after cataract surgery. Animal Studied Prospective study involving 30 eyes of 21 dogs that underwent phacoemulsification.
Kyulee Kim, Young‐Sun Kang, Joon Young Kim   +2 more
wiley   +1 more source