A finite element method for a fourth order surface equation with application to the onset of cell blebbing [PDF]
A variational problem for a fourth order parabolic surface partial differential equation is discussed. It contains nonlinear lower order terms, on which we only make abstract assumptions, and which need to be defined for specified problems.We derive a ...
Dedner, Andreas+2 more
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TGF-b2 induction regulates invasiveness of theileria-transformed leukocytes and disease susceptibility [PDF]
Theileria parasites invade and transform bovine leukocytes causing either East Coast fever (T. parva), or tropical theileriosis (T. annulata). Susceptible animals usually die within weeks of infection, but indigenous infected cattle show markedly reduced
A Moustakas+51 more
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Tumescent Injections in Subcutaneous Pig Tissue Disperse Fluids Volumetrically and Maintain Elevated Local Concentrations of Additives for Several Hours, Suggesting a Treatment for Drug Resistant Wounds. [PDF]
PurposeBolus injection of fluid into subcutaneous tissue results in accumulation of fluid at the injection site. The fluid does not form a pool. Rather, the injection pressure forces the interstitial matrix to expand to accommodate the excess fluid in ...
Dunn, James CY+5 more
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Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle. [PDF]
Migration through 3D constrictions can cause nuclear rupture and mislocalization of nuclear proteins, but damage to DNA remains uncertain, as does any effect on cell cycle.
Bannister+77 more
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Canaloplasty: current value in the management of glaucoma [PDF]
Canaloplasty is a nonpenetrating blebless surgical technique for open-angle glaucoma, in which a flexible microcatheter is inserted within Schlemm's canal for the entire 360 degrees. When the microcatheter exits the opposite end, a 10-0 prolene suture is
Cagini, Carlo+5 more
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A PDE model for bleb formation and interaction with linker proteins [PDF]
The aim of this paper is to further develop mathematical models for bleb formation in cells, including cell-membrane interactions with linker proteins.
Burger, Martin+2 more
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Actomyosin-based Self-organization of cell internalization during C. elegans gastrulation [PDF]
Background: Gastrulation is a key transition in embryogenesis; it requires self-organized cellular coordination, which has to be both robust to allow efficient development and plastic to provide adaptability. Despite the conservation of gastrulation as a
Bao, Zhirong+4 more
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Pediatric Glaucoma: a literature's review and analysis of surgical results [PDF]
The purpose of this paper is to review the surgical options available for the management of pediatric glaucoma, to evaluate their advantages and disadvantages together with their long-term efficacy, all with the intent to give guidelines to physicians on
IACOVELLO, DANIELA+4 more
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A novel function for the Caenorhabditis elegans torsin OOC-5 in nucleoporin localization and nuclear import. [PDF]
Torsin proteins are AAA+ ATPases that localize to the endoplasmic reticular/nuclear envelope (ER/NE) lumen. A mutation that markedly impairs torsinA function causes the CNS disorder DYT1 dystonia. Abnormalities of NE membranes have been linked to torsinA
Dauer, William T+4 more
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A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative [PDF]
Blebbistatin is a commonly used molecular tool for the specific inhibition of various myosin II isoforms both in vitro and in vivo. Despite its popularity, the use of blebbistatin is hindered by its poor water-solubility (below 10 micromolar in aqueous ...
Hegyi, György+9 more
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