IL-6 and PRG4 are novel predictive and mechanistic tissue biomarkers in conjunctival fibrosis [PDF]
, 2017 IMPORTANCE: Postsurgical fibrosis is a critical determinant of the long-term success of glaucoma surgery, but no reliable biomarkers are currently available to stratify the risk of scarring.
Bouremel, Yann +7 more
core +1 more source
Bleb formation in small unruptured intracranial aneurysm as a predictor of early rupture [PDF]
, 2018 Small unruptured aneurysms are thought to have a low risk of rupture, but the management of such lesions is still controversial. A 73-year-old man with a small anterior communication artery aneurysm, 4 mm in diameter, while on follow-up, developed an ...
Ishikawa Eiichi +6 more
core +2 more sources
Consensual ophthalmotonic reaction in Chinese patients following augmented trabeculectomy or ExPRESS shunt implantation [PDF]
, 2016 INTRODUCTION: Consensual ophthalmotonic reaction (COR) was first described in 1924. Studies following monocular application of glaucoma drops and laser trabeculoplasty showed a drop in fellow eye intraocular pressure (IOP).
Chan, JCH +4 more
core +1 more source
Actin at cell-cell junctions is composed of two dynamic and functional populations [PDF]
, 2005 The ability of epithelial cells to polarize requires cell-cell adhesion mediated by cadherin receptors. During cell-cell contact, the mechanism via which a flat, spread cell shape is changed into a tall, cuboidal epithelial morphology is not known.
Bailly, M. +6 more
core +1 more source
Sensing the difference: the influence of anisotropic cues on cell behavior [PDF]
, 2015 From tissue morphogenesis to homeostasis, cells continuously experience and respond to physical, chemical and biological cues commonly presented in gradients.
Ballester-Beltrán, Jose +4 more
core +2 more sources
Quantitative Evaluation of Phase Retardation in Filtering Blebs Using Polarization-Sensitive Optical Coherence Tomography [PDF]
, 2016 journal ...
Beheregaray Simone +8 more
core +1 more source
Integrin-mediated membrane blebbing is dependent on the NHE1 and NCX1 activities. [PDF]
, 2011 Integrin-mediated signal transduction and membrane blebbing have been well studied to modulate cell adhesion, spreading and migration^1-6^. However, the relationship between membrane blebbing and integrin signaling has not been explored.
Chi-Hung Lin +8 more
core +1 more source
Development of targeted siRNA nanocomplexes to prevent fibrosis in experimental glaucoma filtration surgery [PDF]
, 2018 RNA interference induced by double-stranded, small interfering RNA (siRNA) molecules has attracted great attention as a naturally-occurring approach to silence gene expression with high specificity.
Awwad, Sahar +6 more
core +3 more sources
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Advanced Biology, EarlyView.Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz +2 more
wiley +1 more source