Results 31 to 40 of about 13,955 (223)

Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration

open access: yesAdvanced Materials, EarlyView.
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo   +5 more
wiley   +1 more source

Pre-operative intraocular pressure does not influence outcome of trabeculectomy surgery: a retrospective cohort study. [PDF]

open access: yes, 2015
To investigate whether pre-operative intraocular pressure (IOP) predicts outcome of trabeculectomy surgery in patients with primary open angle glaucoma over a 3-year period of follow ...
Martin, KR   +3 more
core   +2 more sources

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

open access: yesAdvanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang   +8 more
wiley   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

open access: yesAdvanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei   +15 more
wiley   +1 more source

Birefringence measurement of cornea and anterior segment by office-based polarizationsensitive optical coherence tomography [PDF]

open access: yes, 2011
We present a case series of cornea and anterior segment disorders investigated by an office-based polarization-sensitive optical coherence tomography (PS-OCT).
Fukuda Shinichi   +10 more
core   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

open access: yesAdvanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao   +17 more
wiley   +1 more source

Recommendations for the management of elevated intraocular pressure due to bleb fibrosis after XEN gel stent implantation

open access: yesClinical Ophthalmology, 2019
Vanessa Vera,1 Arsham Sheybani,2 Dan Lindfield,3 Ingeborg Stalmans,4 Iqbal Ike K Ahmed5 1Department of Glaucoma, Unidad Oftalmologica de Caracas, Caracas, Venezuela; 2Department of Ophthalmology and Visual Sciences, Washington University School of ...
Vera V   +4 more
doaj  

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

open access: yesAdvanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park   +9 more
wiley   +1 more source

Application of 2-octyl-cyanoacrylate for corneal perforation and glaucoma filtering bleb leak

open access: yesClinical Ophthalmology, 2013
Motonori Okabe,1 Kiyotaka Kitagawa,2 Toshiko Yoshida,1 Chika Koike,1 Takeshi Katsumoto,2 Etsuko Fujihara,2 Toshio Nikaido1 1Department of Regenerative Medicine, University of Toyama, Graduate School of Medicine and Pharmaceutical Sciences, Toyama ...
Okabe M   +6 more
doaj  

Effect of Pharmacological Mydriasis on the Intraocular Pressure in Eyes with Filtering Blebs Compared to Normal Eyes: A Pilot Study

open access: yesClinical Ophthalmology, 2022
Hani M Gharieb Ibrahim Ophthalmology Department, Ain Shams University, Cairo, EgyptCorrespondence: Hani M Gharieb IbrahimOphthalmology Department, Ain Shams University Faculty of Medicine, Ramsees Street, Abbaseya, Cairo, Egypt, Email hani.gharieb@med ...
Ibrahim HMG
doaj  

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