Results 91 to 100 of about 1,296,881 (371)

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

open access: yesAdvanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao   +11 more
wiley   +1 more source

Bioprinted Micro‐Clots for Kinetic Analysis of Endothelial Cell‐Mediated Fibrinolysis

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This paper describes the development of a microscale model that quantifies the breakdown of fibrin by endothelial cells. The small size scale of this engineered system enables fibrin breakdown to be observed without the addition of external activators. This system could help in identifying compounds which both promote and hinder thrombosis.
Jonathan J. Chang   +5 more
wiley   +1 more source

Management considerations of massive hemoptysis while on extracorporeal membrane oxygenation. [PDF]

open access: yes, 2016
BACKGROUND: Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is a life-saving procedure in patients with both respiratory and cardiac failure. Bleeding complications are common since patients must be maintained on anticoagulation.
Cavarocchi, Nicholas C.   +5 more
core   +2 more sources

Delivery of Islatravir via High Drug‐Load, Long‐acting Microarray Patches for the Prevention or Treatment of Human Immunodeficiency Virus

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Islatravir‐loaded dissolving microarray patches (MAPs) provide a minimally invasive, long‐acting solution for HIV‐1 prevention and treatment. In rats, sustained islatravir delivery lasts up to three months, while in minipigs, efficacious plasma levels are detected for six days.
Qonita Kurnia Anjani   +11 more
wiley   +1 more source

An In Situ Curing, Shear‐Responsive Biomaterial Designed for Durable Embolization of Microvasculature

open access: yesAdvanced Healthcare Materials, EarlyView.
NeoCast is a next‐generation, solvent‐free, non‐adhesive liquid embolic designed for indications where deep occlusion is desired (e.g., tumors and chronic subdural hematoma). This novel agent offers ideal embolic properties: injectability, controllability, excellent visibility, and biocompatibility.
Quynh P. Pham   +16 more
wiley   +1 more source

1, 2, 3, Stop the Bleed: Analysis of a Bleeding Control Educational Course [PDF]

open access: yes, 2018
Hemorrhaging, or uncontrolled bleeding, accounts for 40% of preventable deaths in the United States that occur after a traumatic injury. The Stop the Bleed campaign was launched in 2015 by the White House National Security Council to educate the public ...
Kramer, RN, Nora   +2 more
core   +1 more source

Notes on Insect Injection, Anesthetization, and Bleeding. [PDF]

open access: yes, 2017
(excerpt) In recent years there has been a burgeoning interest in insect cytogenetics, sometimes involving in vivo cultures of haematocytes for chromosomal analysis.
de Viedma, M. G, Nelson, M. L
core   +3 more sources

Dexamethasone Delivery via Amphiphilic, Low‐swelling Hydrogels Treats Postoperative Inflammation in Cervical Spine Applications

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman   +6 more
wiley   +1 more source

PB2360: QUALITY OF LIFE AND TREATMENT SATISFACTION AMONG PATIENTS UNDER LONG-TERM ANTICOAGULANT THERAPY WITH VITAMIN K ANTAGONISTS

open access: yesHemaSphere, 2022
A. Varaklioti   +8 more
doaj   +1 more source

PHARMACOKINETIC-GUIDED PROPHYLAXIS FOR PEOPLE WITH HEMOPHILIA A

open access: yesHematology, Transfusion and Cell Therapy, 2021
Pharmacokinetic (PK)-guided prophylaxis for people with hemophilia A (PwHA) treatment has been related to fewer bleeding and cost savings have been reported.
ACO Borges   +7 more
doaj  

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