Results 31 to 40 of about 1,063,323 (312)

Assesment of Upper Gastrointestinal Bleeding in the Pediatric Emergency Department [PDF]

open access: yes, 2023
Introduction:Upper gastrointestinal bleeding is an important emergency problem that can occur at any age in childhood and requires urgent treatment for the underlying cause.
Betül Öztürk   +17 more
core   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine   +21 more
wiley   +1 more source

A Pharmacist-Managed Hydroxyurea Prescribing Protocol Improves Uptake and Optimization among Patients with Sickle Cell Disease

open access: yesAdvances in Hematology
Sickle cell disease (SCD) is a common genetic disorder with potentially serious sequelae that can be effectively treated with hydroxyurea. Despite its favorable benefit-risk profile, hydroxyurea uptake in patients with SCD is low.
Cameron Roessner   +4 more
doaj   +1 more source

Prediction of in-hospital bleeding in acutely ill medical patients: External validation of the IMPROVE bleeding risk score [PDF]

open access: yes, 2023
INTRODUCTION Pharmacological thromboprophylaxis slightly increases bleeding risk. The only risk assessment model to predict bleeding in medical inpatients, the IMPROVE bleeding risk score, has never been validated using prospectively collected outcome
Christine Baumgartner   +29 more
core   +2 more sources

Uncovering Inequities: The Role of Social Determinants of Health in Hospitalized Adolescents and Young Adults With Heavy Menstrual Bleeding

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres   +6 more
wiley   +1 more source

At the age of three

open access: yesBleeding, Thrombosis and Vascular Biology
At the age of three, a little boy is able to undress and is starting to dress independently, can eat using a spoon and fork, knows how to hold a pencil correctly, and enjoys drawing vertical, horizontal, and curved lines with pencils and colored crayons.
Giovanni de Gaetano, Chiara Cerletti
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The Bleeding Disorders Research Collaborative

open access: yesBlood Vessels, Thrombosis & Hemostasis
: The Bleeding Disorders Research Collaborative (BDRC) aims to advance an accessible standard of care and quality of life for all people living with inheritable bleeding disorders.
Leonard A. Valentino   +8 more
doaj   +1 more source

To Bleed‐Off or Not to Bleed‐Off?

open access: yesGeophysical Research Letters
Abstract Bleed‐off and shut‐in of injection have been implemented in different Enhanced Geothermal Systems (EGS) in an attempt to mitigate the induced seismicity at and after the injection stop. This article tackles the controversial discussion on the mitigation of the post‐injection induced seismicity through ending fluid injection ...
Boyet, Auregan   +2 more
openaire   +3 more sources

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