Results 41 to 50 of about 1,337,732 (347)
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Predicting Bleeding and Thrombosis Complications in Patients with Continuous Flow Left Ventricular Assist Devices [PDF]
, 2020 Background: Left ventricular assist device (LVAD) therapy has been proven to relieve heart failure symptoms and improve survival, but is not devoid of bleeding and/or thrombotic complications.
Cook, Aaron +6 more
core +1 more source
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
The thrombotic spectrum of B-thalassemia
Thrombosis Update, 2022 B-thalassemia is one of the most common recessive monogenic disorders, characterized by phenotypic diversity, lifelong treatment and severe complications. Apart from anemia, extramedullary erythropoiesis with skeletal deformities, iron overload and organ
Mavra Vasilopoulou +2 more
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South African Medical Journal, 2018 Click on the link to view.S Afr Med J 2018;108(8 ...
Mankahla, Ncedile +2 more
openaire +6 more sources
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
To Bleed‐Off or Not to Bleed‐Off?
Geophysical Research LettersAbstractBleed‐off and shut‐in of injection have been implemented in different Enhanced Geothermal Systems (EGS) in an attempt to mitigate the induced seismicity at and after the injection stop. This article tackles the controversial discussion on the mitigation of the post‐injection induced seismicity through ending fluid injection by either a bleed ...
Auregan Boyet +2 more
openaire +3 more sources
Autonomous Systems as Legal Agents: Directly by the Recognition of Personhood or Indirectly by the Alchemy of Algorithmic Entities [PDF]
, 1999 The clinical manifestations of platelet dense (δ) granule defects are easy bruising, as well as epistaxis and bleeding after delivery, tooth extractions and surgical procedures.
Fagerberg, I. +2 more
core +2 more sources
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
Sengstaken-Blakemore tube as a rescue treatment for hemorrhagic shock secondary to laparoscopic adjustable gastric banding erosion [PDF]
, 2019 Gastrointestinal bleeding is an uncommon but potentially life-threatening complication of laparoscopic adjustable gastric banding (LAGB) erosion. We present the use of a Sengstaken-Blakemore tube as a treatment device for severe gastrointestinal bleeding
Brown +14 more
core +2 more sources